NCT07854990Not yet recruiting
Clinical Predictors and Therapeutic Gaps in CKM Syndrome Among Adults With Type 2 Diabetes
Clinical Predictors and Therapeutic Gaps Across Stages of Cardio-Renal-Metabolic (CKM) Syndrome Among Adults With Type 2 Diabetes: A Cross-Sectional Study
Source: ClinicalTrials.gov · Last updated 2 Oct 2026
Brief summary (registry, in English)
Type 2 diabetes (T2D) is a principal driver of cardiovascular-renal-metabolic (CKM) syndrome, where metabolic, renal, and cardiac dysfunction accelerate disease progression. This cross-sectional study aims to classify adult patients with T2D attending outpatient clinics at Assiut University Hospitals across CKM stages (0-4) according to the 2023 American Heart Association (AHA) staging system. Additionally, the study identifies independent clinical and laboratory predictors of advanced CKM stages (Stages 3-4) and quantifies the therapeutic gap regarding guideline-indicated organ-protective medications (SGLT2 inhibitors, GLP-1 receptor agonists, RAAS inhibitors, statins, and MRAs).
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 231 (estimated)
- First submitted
- 27 Sept 2026
- Start date
- 20 Oct 2026
- Primary completion date
- 20 Mar 2028
- Lead sponsor
- Assiut University
- Diseases
- Chronic kidney disease, Type 2 diabetes
- NCT number
- NCT07854990
What you commit to
- Study type: Observational
- Planned participants: 231
- From 20 Oct 2026 to the primary completion date, 20 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Already on chronic dialysis or with a functioning kidney transplant.
Other illness
- Type 1 or secondary diabetes.
- Active malignancy or terminal illness with life expectancy \<6 months.
Lab values
- Incomplete essential clinical or laboratory data that cannot be obtained at the visit.
Other
- Pregnancy.
Who the study is looking for
- Adults aged 18 years or older.
- Established diagnosis of type 2 diabetes mellitus (ADA criteria) for at least 6 months with diabetic kidney disease (DKD), obesity, or cardiac affection.
- Willing and able to give written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assiut University Coordinator of this site? Confirm its status | Asyut | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.