NCT07855419Recruiting
Sarcopenia and Interlaminar Epidural Steroid Injection Outcomes in Lumbar Spinal Stenosis
Association Between Sarcopenia and Outcomes of Interlaminar Epidural Steroid Injection in Patients With Lumbar Spinal Stenosis: A Prospective Observational Study
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
This prospective observational study aims to investigate the association between sarcopenia and clinical outcomes following interlaminar epidural steroid injection in patients with lumbar spinal stenosis. Patients who are scheduled to undergo interlaminar epidural steroid injection as part of routine clinical care will be enrolled. Before the procedure, sarcopenia-related assessments, including the SARC-F questionnaire, handgrip strength, and the five-times sit-to-stand test, will be performed. Lumbar magnetic resonance imaging (MRI) will also be evaluated for paraspinal muscle characteristics and the severity of lumbar spinal stenosis. Pain intensity, functional status, walking capacity, and health-related quality of life will be assessed at baseline. Pain intensity, functional status, and health-related quality of life will be reassessed at 3 weeks and 3 months after the procedure. The study will evaluate whether sarcopenia and MRI-based paraspinal muscle characteristics are associated with clinical outcomes following interlaminar epidural steroid injection.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 70 (estimated)
- First submitted
- 28 Sept 2026
- Start date
- 2 Oct 2026
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Marmara University
- NCT number
- NCT07855419
What you commit to
- Study type: Observational
- Planned participants: 70
- From 2 Oct 2026 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Lumbar epidural steroid injection within the previous 3 months
- Severe motor deficit or an indication for surgical treatment
Other illness
- History of lumbar fusion surgery
- Polyneuropathy, neuromuscular disease, or neurological disease that may significantly affect muscle mass
- Active malignancy or systemic inflammatory disease
- Cognitive impairment or communication problems that may prevent completion of study assessments
- Coagulopathy or active infection constituting a contraindication to epidural injection
- Inflammatory rheumatic disease requiring chronic corticosteroid therapy
Other
- Prominent radiculopathy due to lumbar disc herniation
- Significant mobility limitation due to advanced hip or knee osteoarthritis
Who the study is looking for
- Clinical and radiological diagnosis of lumbar spinal stenosis
- Persistent symptoms despite conservative treatment and scheduled to undergo interlaminar epidural steroid injection as part of routine clinical care
- Age between 50 and 75 years
- Low back and/or leg pain for at least 3 months
- Availability of lumbar magnetic resonance imaging (MRI)
Age in the registry: 50 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Marmara University Pendik Training and Research Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.