NCT07857044Recruiting
Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities
Left-atrial Fibrosis in Persistent Atrial Fibrillation, Sleep Apnoe and Primary Aldosteronism
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
Pulmonary vein isolation is an established intervention for atrial fibrillation. Patients with a paroxysmal atrial fibrillation have no or only few comorbidities and a good prognosis in respect to their atrial fibrillation. In contrast, patients with persistent atrial fibrillation often suffer from relevant comorbidities and recurrence of atrial fibrillation is common. Left-atrial fibrosis and its electrophysiological consequences are involved in the recurrence rate, but pathophysiological mechanisms are yet to be better characterized. The study investigates relevant comorbidities to elucidated their effect on atrial fibrosis and recurrence rates of atrial fibrillation. Furthermore, the investigators evaluate the prevalence of these comorbidities.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 29 Mar 2023
- Start date
- 31 Mar 2023
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Christina Berr. MD
- Diseases
- Atrial fibrillation
- NCT number
- NCT07857044
What you commit to
- Study type: Observational
- Planned participants: 200
- From 31 Mar 2023 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- medication interfereing with measurements of atrial fibrosis
Other
- valvular atrial fibrillation
- formerly ablation
- known or treated comorbidities (OSAS, PA)
Who the study is looking for
- persistent atrial fibrillation, eligible for ablation
- BMI 19-40
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Augsburg Coordinator of this site? Confirm its status | Augsburg | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.