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NCT07857044Recruiting

Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities

Left-atrial Fibrosis in Persistent Atrial Fibrillation, Sleep Apnoe and Primary Aldosteronism

Source: ClinicalTrials.gov · Last updated 5 Oct 2026

Brief summary (registry, in English)

Pulmonary vein isolation is an established intervention for atrial fibrillation. Patients with a paroxysmal atrial fibrillation have no or only few comorbidities and a good prognosis in respect to their atrial fibrillation. In contrast, patients with persistent atrial fibrillation often suffer from relevant comorbidities and recurrence of atrial fibrillation is common. Left-atrial fibrosis and its electrophysiological consequences are involved in the recurrence rate, but pathophysiological mechanisms are yet to be better characterized. The study investigates relevant comorbidities to elucidated their effect on atrial fibrosis and recurrence rates of atrial fibrillation. Furthermore, the investigators evaluate the prevalence of these comorbidities.

Status (registry)
Recruiting
Study type
Observational
Enrollment
200 (estimated)
First submitted
29 Mar 2023
Start date
31 Mar 2023
Primary completion date
31 Dec 2028
Lead sponsor
Christina Berr. MD
NCT number
NCT07857044

What you commit to

  • Study type: Observational
  • Planned participants: 200
  • From 31 Mar 2023 to the primary completion date, 31 Dec 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • medication interfereing with measurements of atrial fibrosis

Other

  • valvular atrial fibrillation
  • formerly ablation
  • known or treated comorbidities (OSAS, PA)

Who the study is looking for

  • persistent atrial fibrillation, eligible for ablation
  • BMI 19-40

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Hospital Augsburg
Coordinator of this site? Confirm its status
AugsburgGermanyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.