NCT07857200Recruiting
The Use of Risk Prediction to Identify Patients at Risk for Chronic Kidney Disease: Patient and Provider Interventions for Patients at High Risk for Chronic Kidney Disease
The Use of Risk Prediction to Identify Patients at Risk for Chronic Kidney Disease (Short Name: RISK [Risk InterventionS for Chronic Kidney Disease])
Source: ClinicalTrials.gov · Last updated 5 Oct 2026
Brief summary (registry, in English)
This prospective, cluster-randomized trial is structured as a pragmatic study, embedding the outreach intervention within routine clinical workflows. The intervention reflects real-world provider-patient communication methods. The primary research aim is to evaluate, under typical practice conditions, whether structured notification strategies improve follow-up screening. We will evaluate whether targeted provider and patient-directed communication increases completion of CKD disease lab testing (eGFR and uACR) among individuals identified as being at risk for having CKD based on the model developed in in Phase 1. We will identify up to 1,000 patients with high risk of having CKD. All patients' primary care providers (PCPs) will receive a message notifying them of patients' elevated risk status and the recommendation for CKD testing per standard practice. Additionally, we will randomly allocate providers whose patients will receive letters ( \~n=500 patients) and providers whose patients will receive a phone call ( \~n=250 patients).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1500 (estimated)
- First submitted
- 31 Aug 2026
- Start date
- 20 Aug 2026
- Primary completion date
- 20 Aug 2027
- Lead sponsor
- Kaiser Permanente
- Diseases
- Chronic kidney disease
- NCT number
- NCT07857200
What you commit to
- Study type: Interventional
- Planned participants: 1500
- From 20 Aug 2026 to the primary completion date, 20 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- On hospice, or have conditions that indicate end of life (metastatic cancer, on dialysis, etc.)
Lab values
- Patients who have a completed both the eGFR and uACR within the 12 months prior to the date of cohort identification.
Other
- On the research exclusion list between 1/1/2013 and date of the data pull
- Non-English / non-Spanish speaking (those who are excluded from the intervention arm solely due to language barriers will be reported to the IRB at continuing review).
- Pregnant patients.
Who the study is looking for
- At high risk for CKD as determined by CKD model developed in Phase 1
- Age 18-80 as of date of data pull
- At least 12 months of health plan coverage
- Speaks English or Spanish
- We will include both paneled and unpaneled patients
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center for Health Research, Kaiser Permanente NW Coordinator of this site? Confirm its status | Portland | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.