NCT07863180RecruitingPhase 1/2
Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual Trial
Tributyrin for PSP: Phase 1b Virtual Trial - Feasibility Study
Source: ClinicalTrials.gov · Last updated 5 Nov 2026
Brief summary (registry, in English)
This research is studying a supplement called tributyrin in people with Progressive Supranuclear Palsy (PSP) to learn about its safety and tolerability as a potential treatment. The goal of this research study is to see if a similar supplementation regimen and virtual testing is feasible for people with PSP.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- First submitted
- 1 Oct 2026
- Start date
- 1 Oct 2026
- Primary completion date
- May 2027
- Lead sponsor
- Prabesh Kanel
- Diseases
- Parkinson disease
- NCT number
- NCT07863180
What you commit to
- Study type: Interventional · Phase 1/2
- Planned participants: 15
- From 1 Oct 2026 to the primary completion date, May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Regular use of typical anti-cholinergic drugs.
Other illness
- Recent history of significant, uncontrolled GI disease such as Gastroesophageal reflux disease, colorectal cancer.
- Any other condition or criterion that, in the opinion of the investigators, would preclude safe and meaningful participation in the study.
Other
- Significant metabolic or uncontrolled medical comorbidity.
- Women of child-bearing potential, or who are pregnant and/or nursing.
- Suicidal ideation, as indicated by a response of 2 or 3 on question 9 of the Beck Depression Inventory.
Who the study is looking for
- Male or Female, age 45 years and over.
- Diagnosis of PSP-Richardson syndrome (RS) based on Movement Disorder Society (MDS) Criteria, including
- Vertical supranuclear gaze palsy.
- Repeated unprovoked falls OR tendency to fall on the pull test within 3 years.
- Access to the internet and webcam for virtual visits.
- Presence of a caregiver.
Age in the registry: 45 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Domino's Farms Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.