NCT07866144Completed
Prediction of Adverse Events From Non-PCI Coronary Plaques Using Machine Learning
Prediction of Adverse Events From Non-PCI Coronary Plaques Using Machine Learning: the Predict-AI Study
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
The aim of our project is to predict, with the help of artificial intelligence (AI) and machine learning techniques, the natural history of non-flow-limiting coronary stenoses and to develop and validate a machine learning risk score able to estimate the risk of MACE during follow-up based on OCT findings observed on coronary plaques not subjected to percutaneous coronary intervention (PCI) and on the clinical characteristics of the patients. We will collect information on all non-PCI coronary lesions assessed by performing OCT in non-culprit vessels of patients presenting with ACS or Chronic Coronary Syndrome (CCS) at the index procedure. All OCT runs will be digitized and analyzed with the help of AI. The OCT appearance of coronary plaques will be analyzed with AI and correlated with the risk of MACE during follow-up (a composite of cardiac death, myocardial infarction, or target lesion revascularization). An AI predictive risk model based on coronary plaque OCT images and patient clinical characteristics will be developed to estimate the risk of MACE incidence at follow-up. Cutting-edge machine learning algorithms, including convolutional neural networks, random forests, and support vector machines, will be used.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 600 (actual)
- First submitted
- 5 Oct 2026
- Start date
- Jan 2023
- Primary completion date
- Jul 2026
- Lead sponsor
- A.O.U. Città della Salute e della Scienza
- Diseases
- Coronary artery disease
- NCT number
- NCT07866144
What you commit to
- Study type: Observational
- Participants enrolled: 600
- From Jan 2023 to the primary completion date, Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \< 18 Years
Other
- NO STEMI - NSTEMI - CCS - UA
Who the study is looking for
- Age \>18 Years
- STEMI - NSTEMI - CCS - UA
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| AOU Città della Salute e della Scienza Coordinator of this site? Confirm its status | Turin | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.