NCT07866196Not yet recruiting
Prevalence of Asymptomatic Bacteriuria Among Pregnant Women With Pre-eclampsia in Women Health Hospital Assiut University
Prevalence of Asymptomatic Bacteriuria Among Pregnant Women With Pre-eclampsia in Women Health Hospital Assiut University: A Cross-Sectional Study
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
Pre-eclampsia is a hypertensive disorder of pregnancy that can lead to significant health complications for both the mother and the fetus. Asymptomatic bacteriuria (ASB) occurs when significant amounts of bacteria are present in the urinary tract without causing symptoms such as burning, pain, or fever. Research suggests that persistent, asymptomatic bacterial growth can stimulate inflammatory responses and endothelial dysfunction, which may contribute to or worsen pre-eclampsia. However, local data regarding how frequently this condition occurs among pre-eclamptic women in Assiut remains limited. The primary purpose of this cross-sectional study is to determine the prevalence of asymptomatic bacteriuria among pregnant women diagnosed with pre-eclampsia admitted to or attending the Department of Obstetrics and Gynecology at Women's Health Hospital, Assiut University. The study also aims to identify the specific bacterial species responsible for these infections, assess their antibiotic susceptibility profiles, and evaluate potential sociodemographic and clinical risk factors. Enrolled participants will be asked to complete a structured interview questionnaire regarding their medical history, obstetric history, and sociodemographic details. Each participant will provide a single clean-catch midstream urine sample for quantitative urine culture and microbiological analysis. Positive culture results will be communicated to the treating clinical team to guide targeted antibiotic management.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 129 (estimated)
- First submitted
- 4 Oct 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 30 Nov 2027
- Lead sponsor
- Assiut University
- Diseases
- High blood pressure
- NCT number
- NCT07866196
What you commit to
- Study type: Observational
- Planned participants: 129
- From 1 Nov 2026 to the primary completion date, 30 Nov 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of antimicrobial/antibiotic therapy within the preceding 2 weeks prior to recruitment
- Diabetes mellitus with concurrent urinary symptoms
Other illness
- Presence of clinical symptoms of a urinary tract infection
- Documented pre-existing chronic kidney disease
Other
- Known congenital or acquired structural urinary tract abnormalities
- Refusal to provide informed consent or participate in the study
Who the study is looking for
- Pregnant women aged 18 to 45 years
- Gestational age ≥ 20 weeks
- Singleton or multiple pregnancy
- Clinically diagnosed with pre-eclampsia
- Absence of clinical symptoms suggestive of a urinary tract infection (dysuria, urgency, frequency, suprapubic pain, or fever)
- Provision of signed written informed consent
Age in the registry: 18 years to 45 years · Sex: Female
This page is information, not medical advice. Discuss any trial with your doctor.