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NCT07866287Not yet recruiting

Finerenone's Impact on Cardiac Electrical Stability in HFpEF

Impact of Finerenone on Cardiac Electrical Stability in Patients With Heart Failure With Preserved Ejection Fraction

Source: ClinicalTrials.gov · Last updated 8 Oct 2026

Brief summary (registry, in English)

To evaluate the efficacy of finerenone in reducing the incidence of any electrical instability or arrhythmias in the form of new-onset atrial fibrillation or atrial flutter (AFF), atrial tachycardia, extrasystoles (premature atrial and ventricular contractions, PACs and PVCs, respectively), ventricular arrhythmias, bradycardia, in patients with heart failure with preserved ejection fraction who are in sinus rhythm.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
10 Sept 2026
Start date
1 Oct 2026
Primary completion date
1 Sept 2027
Lead sponsor
Assiut University
NCT number
NCT07866287

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 1 Oct 2026 to the primary completion date, 1 Sept 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Any history of documented atrial fibrillation, atrial flutter, or atrial tachycardia.
  • Presence of an implanted cardiac pacemaker or defibrillator with active atrial pacing.
  • Severe liver impairment.

Lab values

  • Estimated glomerular filtration rate (eGFR)\<25 mL/min/1.73m2 at screening.
  • Baseline serum potassium level\>5 mEq/L.

Other

  • Presence of conduction abnormalities such as LBBB or RBBB.
  • Presence of significant valvular dysfunction.
  • Marked electrolyte imbalance.

Who the study is looking for

  • Age ≥ 18 years.
  • Evidenced heart failure with preserved ejection fraction (HFpEF) based on H2FPEF score.
  • Documented sinus rhythm at screening by resting ECG and Holter.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.