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NCT07866872Enrolling by invitation

Blood Volume Monitoring Via Critline in Volume Overload: Hospitalization and Readmission

Source: ClinicalTrials.gov · Last updated 8 Oct 2026

Brief summary (registry, in English)

The investigators are examining how adding relative blood volume monitoring (RBVM) to the best clinical practice affects outcomes (length of stay and rehospitalization) among dialysis patients hospitalized for or with volume overload.

Status (registry)
Enrolling by invitation
Study type
Observational
Enrollment
400 (estimated)
First submitted
29 Sept 2026
Start date
17 Jun 2026
Primary completion date
Jun 2027
Lead sponsor
Massachusetts General Hospital
NCT number
NCT07866872

What you commit to

  • Study type: Observational
  • Planned participants: 400
  • From 17 Jun 2026 to the primary completion date, Jun 2027
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients requiring continuous kidney replacement therapy at admission

Other

  • Patients with acute kidney injury requiring dialysis
  • Patients hospitalized for the initiation of hemodialysis
  • Patients under observation status
  • Patients with liver cirrhosis

Who the study is looking for

  • Maintenance hemodialysis dependent ESRD patients hospitalized for or with volume overload at either MGH or BWH
  • Received at least one hemodialysis session during the index hospitalization
  • Meet the following previously published criteria for volume overload:
    • Clinical impression of volume overload and/or an acute heart failure exacerbation, or b) Respiratory compromise defined as subjective dyspnea or presenting oxygen saturation \<92% on room air plus \>2 of the following signs: i) Jugular venous distension, ii) Third heart sound, iii) Bibasilar lung rales or crackles, iv) Pulmonary edema on chest imaging, v) Reported bilateral pulmonary infiltrates on chest imaging without fever, vi) Reported pleural effusion on chest imaging, vii) Reported abdominal ascites on abdominal imaging, viii) Documented central venous pressure \>12 mmHg, ix) Documented pulmonary capillary wedge pressure \>12 mmHg

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Massachusetts General Hospital
Coordinator of this site? Confirm its status
BostonUnited StatesUnknown status
Brigham and Women's Hospital
Coordinator of this site? Confirm its status
BostonUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.