NCT07869056Completed
Forceps Versus Cryobiopsy in Undiagnosed Exudative Pleural Effusion Using Rigid Thoracoscopy
Comparative Study Between Forceps and Cryobiopsies in Undiagnosed Exudative Pleural Effusion Using Rigid Thoracoscopy
Source: ClinicalTrials.gov · Last updated 9 Oct 2026
Brief summary (registry, in English)
This study compared two ways of taking tissue samples from the lining of the lung (pleura) during rigid thoracoscopy in adults with pleural effusion of unknown cause: conventional forceps biopsy and cryobiopsy (freezing the tissue so a larger sample can be taken). Both methods were used in the same patients during the same procedure. The study looked at how often each method gave a diagnosis, the size and quality of the samples, and side effects such as bleeding and pain.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 1 Oct 2026
- Start date
- 1 Sept 2022
- Primary completion date
- 1 Sept 2024
- Lead sponsor
- Ahmed Zakaria Elsaeed
- Diseases
- Mesothelioma
- NCT number
- NCT07869056
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 1 Sept 2022 to the primary completion date, 1 Sept 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Absolute or relative contraindications for thoracoscopy (coagulation disorders, thrombocytopenia, hemodynamic instability, arrhythmias).
Other
- Diagnosed pleural effusion.
- Uncorrected hypoxemia despite oxygen administration, or oxygen saturation less than 90%.
- Patients who refuse the procedure.
- Small pleural space.
Who the study is looking for
- Patients older than 18 years.
- Undiagnosed exudative pleural effusion.
- No contraindications for thoracoscopy.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| benha University Hospitals Coordinator of this site? Confirm its status | Al Qalyubiyah | Egypt | Unknown status |
| Kafrelsheikh University Hospitals Coordinator of this site? Confirm its status | Sakhā | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.