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NCT07869914Not yet recruiting

Cognitive Intervention for Children and Adolescents With NF1

Feasibility Pilot of a Cognitive Intervention for Children and Adolescents With Neurofibromatosis, Type 1

Source: ClinicalTrials.gov · Last updated 13 Oct 2026

Brief summary (registry, in English)

Psychological interventions have been shown to be effective for managing cognitive and mental health challenges in different patient populations. The investigators are testing whether such a problem-solving skills program is effective and beneficial for children and teens with NF1 when implemented in a real-world setting. Unstuck and On Target! (UOT) is a comprehensive manualized intervention program that targets executive functioning (EF), self-determination, autonomy, quality of life, and mental health, as well as impact on parental stress. It has demonstrated effectiveness at improving EF in youth with autism. The investigators are assessing the effectiveness of the program in youth with NF1 and adapting the program for NF1, as needed, based on participant feedback.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
21 Sept 2026
Start date
28 Sept 2026
Primary completion date
Dec 2028
Lead sponsor
The Hospital for Sick Children
NCT number
NCT07869914

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From 28 Sept 2026 to the primary completion date, Dec 2028
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Conditions that significantly affect cognition (e.g., intellectual disability diagnosis, active psychosis), hearing loss or vision problems precluding participation in group

Other

  • Non-English speaking

Who the study is looking for

  • Receive subject-informed consent;
  • Youth with a diagnosis of NF1 and their parents;
  • Youth aged 8-17 years old (inclusive) and their parents

Age in the registry: 8 years to 17 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.