NCT07869914Not yet recruiting
Cognitive Intervention for Children and Adolescents With NF1
Feasibility Pilot of a Cognitive Intervention for Children and Adolescents With Neurofibromatosis, Type 1
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
Psychological interventions have been shown to be effective for managing cognitive and mental health challenges in different patient populations. The investigators are testing whether such a problem-solving skills program is effective and beneficial for children and teens with NF1 when implemented in a real-world setting. Unstuck and On Target! (UOT) is a comprehensive manualized intervention program that targets executive functioning (EF), self-determination, autonomy, quality of life, and mental health, as well as impact on parental stress. It has demonstrated effectiveness at improving EF in youth with autism. The investigators are assessing the effectiveness of the program in youth with NF1 and adapting the program for NF1, as needed, based on participant feedback.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 21 Sept 2026
- Start date
- 28 Sept 2026
- Primary completion date
- Dec 2028
- Lead sponsor
- The Hospital for Sick Children
- NCT number
- NCT07869914
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 28 Sept 2026 to the primary completion date, Dec 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Conditions that significantly affect cognition (e.g., intellectual disability diagnosis, active psychosis), hearing loss or vision problems precluding participation in group
Other
- Non-English speaking
Who the study is looking for
- Receive subject-informed consent;
- Youth with a diagnosis of NF1 and their parents;
- Youth aged 8-17 years old (inclusive) and their parents
Age in the registry: 8 years to 17 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.