NCT07870655Enrolling by invitation
Long-term Effects and Maintenance of Exercise Habits in Individuals With COPD
Long-term Effects and Maintenance of Exercise Habits in Individuals With COPD: A Follow-up Study of a Clinical Exercise Trial
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
The study aims to evaluate exercise habits and relevant health outcomes at 6 months and again 12 to 18 months after participation in the COPDEX trial (NCT06551441). Specifically, we will investigate the extent to which participants maintain regular exercise in the absence of supervision, how long-term exercise behaviour is associated with quality of life and physical capacity, and identify key motivational facilitators and barriers associated with sustained exercise participation Primary objective is to investigate health-related quality of life in individuals with COPD at 6 months and again 12 to 18 months after participation in the COPDEX trial. Secondary objectives is to investigate exercise habits, physical activity levels, cardiorespiratory fitness, lung function, functional exercise capacity, and body composition in individuals with COPD 6 months and again 12 to 18 months after participation in the COPDEX trial; to explore differences in long-term outcomes according to original allocation in the COPDEX trial; to identify motivational facilitators and barriers associated with the initiation and maintenance of regular exercise following participation in the COPDEX trial. At completion of the randomised controlled exercise trial COPDEX (protocol no. H-24021751), which examined the effects of 6 months of high-intensity interval training (HIIT; three sessions per week) compared with usual activity, all participants were encouraged to either continue or initiate regular exercise. All previous participants will be invited to participate in the present follow-up study, irrespective of their original allocation (HIIT group or usual activity group).
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 66 (estimated)
- First submitted
- 6 Oct 2026
- Start date
- 15 Oct 2026
- Primary completion date
- 30 May 2027
- Lead sponsor
- Copenhagen University Hospital, Rigshospitalet
- Diseases
- COPD
- NCT number
- NCT07870655
What you commit to
- Study type: Observational
- Planned participants: 66
- From 15 Oct 2026 to the primary completion date, 30 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- There are no exclusion criteria for participation in the follow-up study. Prior to the study visit, participants will undergo a medical interview and examination. Participants with contraindications to specific study procedures will remain enrolled in the study but will not undergo the relevant assessments.
- Recent thoracic, abdominal, cerebral, or ophthalmic surgery where forced expiratory manoeuvres may compromise recovery
Other illness
- Symptoms suggestive of unstable ischaemic heart disease
- Acute myocardial infarction within the preceding 3 months
- Uncontrolled cardiac arrhythmias
- Decompensated heart failure
- Severe symptomatic valvular heart disease
- Uncontrolled arterial hypertension (\>180/110 mmHg at rest)
- Acute respiratory infection or COPD exacerbation within the preceding 2 weeks
- Severe musculoskeletal, neurological, or cognitive conditions precluding safe test performance
- Any other condition judged by the study physician to make participation unsafe
- Lung function testing will be performed according to current ATS/ERS recommendations. Contraindications to spirometry and other forced expiratory manoeuvres are:
- Acute myocardial infarction within the preceding month
- Unstable angina
- Acute respiratory infection judged by the study physician to make testing unsafe.
- Any other condition judged by the study physician to make testing unsafe
- Participants unable to perform pulmonary function testing or spirometry may still participate in all other assessments considered safe and feasible.
Other
- Contraindications to cardiopulmonary exercise are:
- Acute pulmonary embolism
- Current pneumothorax
- Active haemoptysis of unknown origin
- Thoracic, abdominal, or cerebral aneurysm judged to be at risk from increased intrathoracic pressure
Who the study is looking for
- Participated in the clinical trial The COPDEX study. Exclusion criteria
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre for Physical Activity Research, Copenhagen University Hospital Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.