NCT07871188Recruiting
Association Between Intraoperative Pulse Pressure Variation and Postoperative Lactate Clearance in Cardiac Surgery
Evaluation of the Relationship Between Intraoperative Pulse Pressure Variation and Postoperative Lactate Clearance in Patients Undergoing Cardiac Surgery
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
This study aims to evaluate the relationship between intraoperative pulse pressure variation (PPV) and postoperative lactate clearance in adult patients undergoing elective cardiac surgery. Intraoperative PPV values will be recorded, and blood lactate levels will be measured at admission to the intensive care unit and at 6 and 12 hours postoperatively. The study will investigate whether intraoperative PPV is associated with postoperative lactate clearance. This is a prospective observational study, and no additional interventions will be performed beyond routine clinical care.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 6 Oct 2026
- Start date
- 2 Oct 2026
- Primary completion date
- 1 Apr 2027
- Lead sponsor
- Elzem SEN
- Diseases
- Coronary artery disease
- NCT number
- NCT07871188
What you commit to
- Study type: Observational
- Planned participants: 100
- From 2 Oct 2026 to the primary completion date, 1 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving off-pump CABG.
Other illness
- Patients with cardiac arrhythmias that may interfere with PPV measurement, such as atrial fibrillation.
- Patients undergoing emergency cardiac surgery.
Other
- Patients with severe aortic regurgitation.
- Patients requiring spontaneous breathing or low tidal volume ventilation (\<6 mL/kg) during PPV measurement.
- Patients with missing or insufficient intraoperative hemodynamic or postoperative lactate measurements.
Who the study is looking for
- Adults aged 18-80 years.
- Patients undergoing elective coronary artery bypass graft (CABG) surgery.
- Patients receiving invasive arterial blood pressure monitoring and mechanical -ventilation during surgery.
- Patients planned for postoperative admission to the intensive care unit.
- Patients whose informed consent has been obtained.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gaziantep University Hospital Coordinator of this site? Confirm its status | Gaziantep | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.