NCT07872319Completed
Biomarkers Usefulness in the Screening of Hepatocellular Carcinoma in an European High-risk Cohort.
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
Longitudinal, prospective, observational, non-interventional study, to evaluate the performance of tumour biomarkers Alpha-fetoprotein (AFP), Lens culinaris-agglutinin-reactive fraction of AFP (AFP-L3), and protein induced by vitamin K absence or antagonist-II (PIVKA-II) and their combinations (GAAD and GALAD algorithms) in the screening of HCC.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 417 (actual)
- First submitted
- 7 Oct 2026
- Start date
- 2 Feb 2022
- Primary completion date
- 31 Jul 2025
- Lead sponsor
- Hospital Universitario La Paz
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT07872319
What you commit to
- Study type: Observational
- Participants enrolled: 417
- From 2 Feb 2022 to the primary completion date, 31 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Child-Pugh C class (except liver transplant eligibility).
- Ingestion of drugs such as warfarin or medications containing vitamin K preparations.
Other
- Pregnancy, past or present germ cell tumours, obstructive jaundice, intrahepatic cholestasis causing chronic decrease in vitamin K.
Who the study is looking for
- Informed consent signed
- EASL recommendations of HCC surveillance
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Universitario La Paz Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.