NCT07873021Active, not recruiting
Percutaneous Portal Vein Recanalization for Refractory Portal Hypertension in Children With Non-Cirrhotic Extrahepatic Portal Vein Obstruction
Percutaneous Portal Vein Recanalization (PVR) by Interventional Radiology for the Management of Refractory Portal Hypertension in Children With Non-cirrhotic Extrahepatic Portal Vein Obstruction.
Source: ClinicalTrials.gov · Last updated 14 Oct 2026
Brief summary (registry, in English)
This monocentric, prospective, observational study aims to evaluate the clinical efficacy, safety, and technical success of percutaneous portal vein recanalization (PVR) performed via interventional radiology. The procedure targets pediatric patients suffering from refractory portal hypertension due to non-cirrhotic extrahepatic portal vein obstruction (EHPVO) who are either ineligible for, or unwilling to undergo, standard physiological surgical options such as the Meso-Rex bypass.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 33 (actual)
- First submitted
- 25 Sept 2026
- Start date
- 1 Jan 2022
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- Papa Giovanni XXIII Hospital
- Diseases
- High blood pressure
- NCT number
- NCT07873021
What you commit to
- Study type: Observational
- Participants enrolled: 33
- From 1 Jan 2022 to the primary completion date, 30 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Primary hepatocellular disease (infectious or any other)
Other
- Any technical contraindication to PVR
- Histology proven fibrosis/cirrhosis (clinically significant \>=F2)
Who the study is looking for
- \< 18-year-old patients (with exception of patients \> 17-year-old if they had a history of non-cirrhotic EHPVO since infancy)
- Portal hypertension resulting from non-cirrhotic EHPVO defined by the presence of at least one of the following: clinical hypersplenism; platelet count \< 150,000 platelets per microliter; history of high risk or bleeding gastrointestinal varices
- Patients not eligible for, or not willing to undergo Meso-Rex bypass surgery
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ASST PAPA GIOVANNI XXIII - Piazza OMS-1, 24127 Bergamo Coordinator of this site? Confirm its status | Bergamo | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.