NCT07877116Not yet recruitingPhase 4
Sevoflurane Versus Propofol Anesthesia in Intracardiac Echocardiography-Guided Atrial Fibrillation Ablation
Comparison of Inhalational Anesthesia and Intravenous Anesthesia as General Anesthesia Management in Intracardiac Echocardiography-Guided Radiofrequency Catheter Ablation Procedures in Patients With Atrial Fibrillation in Terms of Acute Procedural Success and Early Atrial Arrhythmia Recurrence
Source: ClinicalTrials.gov · Last updated 16 Oct 2026
Brief summary (registry, in English)
This prospective, randomized, single-center study will compare sevoflurane inhalational anesthesia with propofol intravenous anesthesia in patients undergoing intracardiac echocardiography-guided radiofrequency catheter ablation for atrial fibrillation. Eligible participants will be randomly assigned to one of two general anesthesia groups. In the sevoflurane group, anesthesia will be maintained with sevoflurane, while in the propofol group, anesthesia will be maintained with propofol administered using target-controlled infusion. In both groups, anesthesia depth will be adjusted to maintain a Bispectral Index value between 40 and 60. The study will evaluate acute procedural success and atrial arrhythmia recurrence at 6 months. Additional outcomes will include mapping time, ablation time, total procedure time, hemodynamic instability, recovery score, and procedural complications.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 124 (estimated)
- First submitted
- 1 Oct 2026
- Start date
- 1 Oct 2026
- Primary completion date
- 30 Apr 2027
- Lead sponsor
- Hüseyin Ulaş Pinar
- Diseases
- Atrial fibrillation
- NCT number
- NCT07877116
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 124
- From 1 Oct 2026 to the primary completion date, 30 Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous catheter ablation.
Other illness
- Known allergy to propofol.
- Known allergy to sevoflurane.
Lab values
- Left ventricular ejection fraction below 35%.
Age
- Patients aged 65 to 90 years with a Mini-Mental State Examination score below 24.
Other
- Emergency ablation procedure.
- Refusal to provide informed consent for study participation.
Who the study is looking for
- Patients diagnosed with atrial fibrillation who are scheduled to undergo elective intracardiac echocardiography-guided radiofrequency catheter ablation.
- Patients aged 18 to 64 years who provide informed consent to participate in the study.
- Patients aged 65 to 90 years with a Mini-Mental State Examination score of 24 or higher who provide informed consent to participate in the study.
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hacettepe University Faculty of Medicine, Department of Anesthesiology and Reanimation Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.