NCT07877298Not yet recruiting
Within-Session Repeatability of EUS-Guided Portal Pressure Gradient Measurement
Within-Session Repeatability and Inter-Operator Reproducibility of EUS-Guided Portal Pressure Gradient Measurement: A Prospective Multicentre Study
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
This prospective multicentre observational reliability study will determine how much a repeated endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement differs from the first measurement in the same patient during the same procedural session. Each participant will undergo two complete EUS-PPG measurement sets using an identical 22-gauge measurement setup. The study will quantify within-session repeatability when the same expert performs both sets and inter-operator reproducibility when different operators perform the sets.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 8 Oct 2026
- Start date
- Jan 2027
- Primary completion date
- Jul 2028
- Lead sponsor
- University Hospital Muenster
- Diseases
- High blood pressure
- NCT number
- NCT07877298
What you commit to
- Study type: Observational
- Planned participants: 150
- From Jan 2027 to the primary completion date, Jul 2028
- 5 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Non-correctable coagulation disorder
Other
- Contraindication to endoscopy, sedation, or endosonography-guided vascular puncture
- Hemodynamic instability at the time of the procedure
- Any intervention between the two measurement sets that may alter portal pressure, including fluid administration beyond maintenance requirements, vasoactive substances, paracentesis, or variceal band ligation
- Technically non-evaluable first measurement set
- Pregnancy or breastfeeding
- Inability to provide informed consent
Who the study is looking for
- Age 18 years or older
- Clinical indication for EUS-guided portal pressure gradient measurement established independently of the study
- Written informed consent, including consent for the additional measurement set
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UZ Leuven Coordinator of this site? Confirm its status | Leuven | Belgium | Unknown status |
| Centre Hospitalier de l'Universite de Montreal (CHUM) Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| McGill University Health Centre Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
| University hospital Muenster Coordinator of this site? Confirm its status | Münster | Germany | Unknown status |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.