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NCT07877493Not yet recruiting

Psychological Support for Chronic Migraine Patients Treated With Anti-CGRP (Anti-Calcitonin Gene-Related Peptide ) Monoclonal Antibodies

Psychological Adjustment Following Extreme Therapeutic Responses to Anti-Calcitonin Gene-Related Peptide (CGRP) Treatment in Patients With Chronic Migraine: A Mixed Quantitative and Qualitative Study

Source: ClinicalTrials.gov · Last updated 16 Oct 2026

Brief summary (registry, in English)

Chronic migraine is a disabling neurological condition that can significantly affect quality of life, emotional well-being, social participation, and daily functioning. Although anti-CGRP monoclonal antibodies have substantially improved migraine management for many patients, little is known about the psychological experiences and adjustment processes associated with these treatments. This observational study aims to explore the psychological adaptation of adults with chronic migraine treated with anti-CGRP monoclonal antibodies. Participants will complete standardized questionnaires assessing migraine-related disability, headache impact, anxiety and depressive symptoms, quality of life, and treatment experiences at treatment initiation and after 12 months of follow-up. Psychological interviews will also be conducted to explore patients' perceptions, coping strategies, and lived experiences of treatment. The study seeks to identify factors associated with positive or negative psychological adaptation to treatment and to better understand patients' emotional experiences throughout their care pathway. The findings may contribute to the development of tailored psychological support interventions for individuals living with chronic migraine.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
30 (estimated)
First submitted
25 Sept 2026
Start date
Oct 2026
Primary completion date
Oct 2026
Lead sponsor
Central Hospital, Nancy, France
Diseases
Migraine
NCT number
NCT07877493

What you commit to

  • Study type: Observational
  • Planned participants: 30
  • From Oct 2026 to the primary completion date, Oct 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \-

Who the study is looking for

  • • Diagnosis of chronic migraine established by a neurologist.
    • Treatment with an anti-CGRP monoclonal antibody administered at the CHRU de Nancy.
    • Completion of the initial psychological interview.
    • Availability of analyzable clinical and psychological data.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHRU
Coordinator of this site? Confirm its status
NancyFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.