NCT07878104Recruiting
Modified Ketogenic Diet on Drug-Resistant Epilepsy in Adults - a Prospective Observational Study of Real-world Data
Source: ClinicalTrials.gov · Last updated 16 Oct 2026
Brief summary (registry, in English)
The purpose of our study is to investigate how dietary treatment with a modified ketogenic diet for patients with drug-resistant epilepsy affects patients' health-related quality of life and seizure frequency. We will also examine the diet's impact on cognitive functions, sleep, treatment side effects, microbiota metabolites, inflammation, and changes in the gut and oral bacterial flora, as well as the long-term aspects of this dietary treatment.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 18 Sept 2026
- Start date
- 10 Oct 2025
- Primary completion date
- Dec 2035
- Lead sponsor
- Karolinska Institutet
- Diseases
- Epilepsy
- NCT number
- NCT07878104
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 10 Oct 2025 to the primary completion date, Dec 2035
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Lack of motivation to treatment with modified ketogenic diet
Other illness
- Severe psychiatric comorbidity , dementia, or severe functional impairment impacting adherence without a next of kin for support with diet.
- Type 1 Diabetes
- Gallbladder disease
- Liver disease
- Metabolic disease
- Kidney disease
Other
- Pregnancy
- Body mass index (BMI) below 19
Who the study is looking for
- Age 18 years or older.
- Drug-resistant epilepsy (seizures not adequately controlled despite two or more antiepileptic drugs at adequate doses)
- Historical seizure frequency of six or more per year
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Karolinska Institutet Coordinator of this site? Confirm its status | Stockholm | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.