NCT07878884Recruiting
PBMT Associated With a Pulmonary Rehabilitation Program on the Functional Capacity of Patients With COPD
Photobiomodulation Therapy (PBMT) Associated With a Pulmonary Rehabilitation Program on the Functional Capacity of Patients With Chronic Obstructive Pulmonary Disease (COPD): a Randomized, Placebo-controlled, Double-blind Clinical Trial.
Source: ClinicalTrials.gov · Last updated 16 Oct 2026
Brief summary (registry, in English)
This study aims to evaluate the effectiveness of photobiomodulation therapy (PBMT) as an adjunct to the pulmonary rehabilitation program on the functional capacity of patients with COPD. This is a randomized, placebo-controlled, double-blind clinical trial conducted with 20 patients from the outpatient clinic of the Integrated Cardiopulmonary and Metabolic Rehabilitation Service of Santa Casa de Porto Alegre. Patients will be allocated to the active PBMT group, receiving photobiomodulation treatment prior to the exercise protocol of the pulmonary rehabilitation program, in the respiratory and peripheral muscles, or the placebo group, which will receive the therapy application at the same points but without the therapeutic dose, prior to rehabilitation. Sixteen PBMT applications will be performed over eight weeks, with a frequency of twice a week. The exercises performed in the institution's pulmonary rehabilitation program by the patients will not be interfered with by the researchers. Evaluations will be carried out in three stages: immediately after recruitment, after 8 interventions, and after 16 interventions.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 2 Jul 2026
- Start date
- 1 Oct 2026
- Primary completion date
- 26 Oct 2026
- Lead sponsor
- Federal University of Health Science of Porto Alegre
- Diseases
- COPD
- NCT number
- NCT07878884
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 1 Oct 2026 to the primary completion date, 26 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent skin lesions or tattoos at the site of therapy application.
Other illness
- Patients with sequelae of stroke;
- Recent acute myocardial infarction (within two months);
- Uncontrolled hypertension;
- Heart failure grade IV according to the New York Heart Association or decompensated;
- Unstable angina or arrhythmia;
- Peripheral vascular alterations in lower limbs such as deep vein thrombosis;
- Disabling osteoarticular or musculoskeletal disease;
- Patients with cancer and/or undergoing cancer treatment;
- Pacemaker or cardiac defibrillator;
Other
- Cognitive dysfunction that prevents the completion of assessments, as well as inability to understand and sign the informed consent form (ICF);
- Patients with systemic lupus erythematosus;
- Hemophilia;
Who the study is looking for
- Patients diagnosed with COPD, in the maintenance phase, with GOLD classification 3 and 4;
- Ability to walk.
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Santa Casa de Porto Alegre Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.