NCT07879950Not yet recruiting
Local Vibration and Ankle Mobilization in Multiple Sclerosis
Effects of Local Vibration and Ankle Joint Mobilization on Muscle Tone, Proprioception, and Balance in Individuals With Multiple Sclerosis: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 19 Oct 2026
Brief summary (registry, in English)
This study will investigate the effects of local vibration and ankle joint mobilization on muscle tone, proprioception, and balance in individuals with multiple sclerosis (MS). Participants will be randomly assigned to one of two treatment groups. One group will receive local vibration applied to the gastrocnemius muscle, while the other group will receive ankle joint mobilization. Both interventions will be performed three times per week for six weeks. Muscle tone, ankle joint position sense, and balance will be assessed before and after the intervention. The study aims to determine whether these interventions can improve neuromuscular and balance-related functions in individuals with MS.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 8 Sept 2026
- Start date
- 15 Dec 2026
- Primary completion date
- 15 May 2027
- Lead sponsor
- Gaziantep Islam Science and Technology University
- Diseases
- Multiple sclerosis
- NCT number
- NCT07879950
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 15 Dec 2026 to the primary completion date, 15 May 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- MS relapse within the previous 3 months.
Other illness
- Severe cognitive impairment or cognitive problems that may interfere with communication or participation.
- History of orthopedic surgery involving the lower extremity or presence of a severe orthopedic condition affecting lower-extremity function.
- Vestibular system disorder or another neurological condition that may affect balance.
- Any medical condition contraindicating local vibration or manual therapy.
Other
- Inability to participate regularly throughout the study period.
Who the study is looking for
- Age between 18 and 65 years.
- Diagnosis of multiple sclerosis confirmed by a neurologist.
- Expanded Disability Status Scale (EDSS) score ≤6.0.
- Ability to walk at least 100 meters, with or without an assistive device.
- No MS relapse within the previous 3 months.
- Willingness to participate in the study and provision of written informed consent.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.