NCT07880730Not yet recruiting
Right Heart Injury Monitoring on ECMO
Feasibility Study for Monitoring Right Ventricular Injury in Patients With Severe Acute Respiratory Failure Supported With Veno-venous Extracorporeal Membrane Oxygenation
Source: ClinicalTrials.gov · Last updated 19 Oct 2026
Brief summary (registry, in English)
This study aims to find out whether it is practical to introduce a consistent monitoring approach to the right side of the heart in patients supported with VV-ECMO. VV-ECMO is a life support machine that takes over the work of the lungs to give them time to recover. It is used when lung injury is life-threatening. Whilst receiving VV-ECMO support, in addition to the current standard of care, the following will be performed twice weekly: * Heart scan (echocardiogram) * Blood tests (hs-troponin and NT-proBNP) The patient's involvement in the study lasts for as long as they are on the life support machine, plus one final heart scan 48 hours after it is removed.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 30 (estimated)
- First submitted
- 12 Oct 2026
- Start date
- Nov 2026
- Primary completion date
- Jan 2028
- Lead sponsor
- Papworth Hospital NHS Foundation Trust
- Diseases
- Heart failure
- NCT number
- NCT07880730
What you commit to
- Study type: Observational
- Planned participants: 30
- From Nov 2026 to the primary completion date, Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients that had been previously included in this study
- Patients requiring VV-ECMO support post pulmonary thrombo-endarterectomy, as a bridge to lung transplantation or post lung-transplantation
Age
- Patients \<18 years old
Other
- Any other reason for VV-ECMO support that is not SARF
- Patients and/or Personal Consultee not fluent in English
Who the study is looking for
- Adults (≥18 years old)
- Less than 72 hours after being established on VV-ECMO due to SARF (either retrieved to RPH from another hospital or already an inpatient at RPH)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Royal Papworth Hospital NHS Foundation Trust Coordinator of this site? Confirm its status | Cambridge | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.