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NCT07881133Recruiting

Perioperative Biomarkers in Colorectal and Gastric Cancer Surgery

Temporal Profiles of Inflammatory Markers in General Oncologic Surgery

Source: ClinicalTrials.gov · Last updated 19 Oct 2026

Brief summary (registry, in English)

This study aims to evaluate whether monitoring perioperative inflammatory and metabolic biomarkers can help identify postoperative complications early in adult patients undergoing colorectal or gastric cancer surgery. The study is a randomized controlled trial conducted at Bucharest Emergency Clinical Hospital, Romania. Participants are assigned to either an intervention group receiving enhanced recovery care (ERAS) combined with perioperative biomarker monitoring or a control group receiving standard postoperative care. The biomarkers of interest include procalcitonin, lactate, and blood glucose. The study will examine their relationship with postoperative complications, particularly infections and anastomotic leakage. Participants will be followed for 30 days after surgery to assess postoperative complications, hospital length of stay, readmissions, and mortality. The findings may help improve postoperative monitoring and support earlier recognition of complications in patients undergoing cancer surgery.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
320 (estimated)
First submitted
12 Oct 2026
Start date
25 Feb 2026
Primary completion date
Jan 2029
Lead sponsor
Bucharest Emergency Hospital
NCT number
NCT07881133

What you commit to

  • Study type: Interventional
  • Planned participants: 320
  • From 25 Feb 2026 to the primary completion date, Jan 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patients with known autoimmune or immunological diseases that may significantly influence inflammatory biomarker levels.
  • Patients diagnosed with inflammatory bowel disease (IBD).

Other

  • Patients who refuse to participate or do not provide written informed consent.

Who the study is looking for

  • Adult patients aged 18 years or older.
  • Patients diagnosed with colorectal or gastric cancer.
  • Patients scheduled for elective abdominal oncologic surgery.
  • Patients classified as ASA physical status II-IV.
  • Patients who provide written informed consent to participate in the study.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Emergency Clinical Hospital Bucharest
Coordinator of this site? Confirm its status
BucharestRomaniaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.