NCT07882550Completed
Validation of Cor-IS Impedance Spectroscopy Against Ultrasound Flow-Mediated Dilation
A Single-Center, Observational Study Evaluating the Cor-IS Impedance Spectroscopy Technique Against Ultrasound Imaging Using Flow-Mediated Dilation Protocol in Healthy Individuals and Patients With Intermediate and Severe Endothelial Dysfunction
Source: ClinicalTrials.gov · Last updated 20 Oct 2026
Brief summary (registry, in English)
This prospective observational study evaluated the Cor-IS bioelectrical impedance spectroscopy technique for the assessment of endothelial function by comparison with ultrasound-based brachial artery flow-mediated dilation (FMD). A total of 208 participants were enrolled and classified into three groups according to their cardiovascular profile: healthy controls, individuals with cardiovascular risk factors, and patients with acute myocardial infarction. Each participant underwent endothelial function assessment using both ultrasound-based FMD and the Cor-IS technique under standardized conditions. The primary objective was to evaluate the correlation and agreement between measurements obtained using Cor-IS and ultrasound-based FMD. Secondary objectives included comparing endothelial function measurements across the three study groups and evaluating their associations with selected clinical and demographic characteristics.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 208 (actual)
- First submitted
- 29 Sept 2026
- Start date
- 1 Sept 2021
- Primary completion date
- 1 Apr 2026
- Lead sponsor
- Aristotle University Of Thessaloniki
- NCT number
- NCT07882550
What you commit to
- Study type: Observational
- Participants enrolled: 208
- From 1 Sept 2021 to the primary completion date, 1 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active cancer.
- Diagnosed psychiatric disorders.
- Non-sinus cardiac rhythm.
- Presence of a cardiac pacemaker.
- Hemodynamic instability, defined as resting heart rate greater than 110 beats/min or systolic/diastolic blood pressure greater than 170/100 mmHg.
Other
- Pregnancy.
Who the study is looking for
- Adult participants able to provide participation consent.
- Healthy controls: no history or evidence of cardiovascular or metabolic disease based on medical history, clinical examination, and laboratory evaluation.
- Cardiovascular risk factor group: presence of at least one established cardiovascular risk factor, including arterial hypertension, diabetes mellitus, or dyslipidemia.
- Acute myocardial infarction group: confirmed diagnosis of acute myocardial infarction based on clinical presentation and cardiac biomarkers, with coronary angiography when available.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ιppokratio General Hospital of Thessaloniki Coordinator of this site? Confirm its status | Thessaloniki | Greece | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.