NCT07882784Not yet recruiting
Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
CrossReg-4-Health: A Multicentre Prospective Cohort Study of Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Source: ClinicalTrials.gov · Last updated 20 Oct 2026
Brief summary (registry, in English)
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited. CrossReg-4-Health is a prospective, multicentre observational cohort study that will enrol 300 consecutive adults with acute spontaneous ICH at three hospitals in Slovenia and Austria. During hospitalisation, the study will collect clinical data, standardised neurological and pain assessments, routine laboratory results, CT, CT angiography and MRI findings, and two research blood samples for biomarkers of brain injury, inflammation, coagulation and pain. Participants will be followed up at 6 and 12 months for survival, functional outcome, neurological status, pain, health-related quality of life, rehabilitation use and readmissions. The main aim is to develop a multimodal prognostic model for functional outcome (modified Rankin Scale) 12 months after ICH.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 12 Oct 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 31 Oct 2028
- Lead sponsor
- University Medical Centre Maribor
- Diseases
- Stroke
- NCT number
- NCT07882784
What you commit to
- Study type: Observational
- Planned participants: 300
- From 1 Nov 2026 to the primary completion date, 31 Oct 2028
- 3 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Intracerebral haemorrhage secondary to head trauma
- Haemorrhage due to an intracranial neoplasm
- Isolated subarachnoid haemorrhage or another primary type of intracranial haemorrhage
Other
- Expected survival of less than 24 hours due to non-neurological comorbidity
- End-of-life care decision already made at presentation
- Withdrawal of consent or major protocol violation
Who the study is looking for
- Age 18 years or older
- Acute spontaneous (non-traumatic) intracerebral haemorrhage confirmed by non-contrast CT or MRI
- Admission during the acute phase of haemorrhage to one of the participating centres
- Written informed consent from the patient or, if the patient lacks capacity, consent from a legally authorised representative
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| LKH-Universitätsklinikum Graz, Medical University of Graz Coordinator of this site? Confirm its status | Graz | Austria | Unknown status |
| Klinikum Klagenfurt am Worthersee Coordinator of this site? Confirm its status | Klagenfurt | Austria | Unknown status |
| University Medical Centre Maribor, Department of Neurology Coordinator of this site? Confirm its status | Maribor | Slovenia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.