NCT07883174Completed
Motion Capture in Box and Bloks Test
Pilot Study Analyzing Upper Limb Kinematics With Motion Capture During the Box and Blocks Test: Normative Data and Data From Subjects With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 20 Oct 2026
Brief summary (registry, in English)
This study aims not only to develop a standardized protocol for performing the targeted BBT but also to assess synchronized parameters: kinematic (using IMUs) and electrophysiological (EMG) data. In this context, the pilot study aims to standardize the instrumented BBT for the objective evaluation of joint kinematics and muscle activations in the upper limb of healthy subjects. After establishing normative movement data, the study will focus on characterizing pathological upper limb movements in individuals with Parkinson's disease and post-stroke, comparing the obtained data with normative references.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 105 (actual)
- First submitted
- 11 Jun 2026
- Start date
- 12 Jan 2020
- Primary completion date
- 14 Jan 2025
- Lead sponsor
- IRCCS San Raffaele Roma
- Diseases
- Stroke, Parkinson disease
- NCT number
- NCT07883174
What you commit to
- Study type: Observational
- Participants enrolled: 105
- From 12 Jan 2020 to the primary completion date, 14 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous brain surgery.
- Stroke group (SG)
Other illness
- coexisting disabling neurological or orthopedic disorders at upper limb;
- severe visual impairment;
Other
- having pathologies affecting the upper limb function;
- having cognitive and/or severe visual deficit.
- Parkinson group (PG)
- inability to understand study instructions;
- severe visual deficit;
- motor and cognitive inability to maintain the correct position during the execution time of the motor task;
- upper limb pain;
- site of the lesion according to Bamford's classification: posterior circulation infarct (POCI) and lacunar infarct (LACI).
Who the study is looking for
- Age between 35 and 85 years old;
- Right-handed.
- diagnosis of idiopathic PD by UK Brain Bank criteria;
- Hoehn and Yahr (H\&Y) stage 2-3;
- aged between 35 and 85 years old;
- moderate disease-related upper limb motor performance deficit (i.e., Unified Parkinson's Disease Rating Scale (UPDRS) Part II, items 8, 9, 10, 11, 12, 16 =2-3; Unified Parkinson's Disease Rating Scale (UPDRS) Part III, items 20, 21, 22, 23, 24, 25 =2-3).
- hemiparesis evaluated
- Fugl-Meyer Assessment Upper Limb (FMA-UL) ranging between moderate (22\<FMA-UL\<44) to mild (FMA\>44);
- site of the cortical/subcortical lesion according to Bamford's classification: total anterior circulation infarct (TACI) and partial rior circulation infarct (PACI).
Criteria the registry did not label
- All participants who have signed the informed consent for the study and meeting the inclusion and exclusion criteria will be considered eligible. Each of the participants belonging to the three groups has to meet the following inclusion and exclusion criteria:
- Control group (CG)
Age in the registry: 35 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS San Raffaele Coordinator of this site? Confirm its status | Roma | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.