NCT07884214Enrolling by invitation
Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer
Nutritional Therapy in the Surgical Prehabilitation of Patients With Esophageal, Gastric, and Pancreatic Cancer to Assess the Reduction of Postoperative Complications and the Maintenance of Muscle Mass.
Source: ClinicalTrials.gov · Last updated 20 Oct 2026
Brief summary (registry, in English)
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after upper GI surgery. However, clinical evidence is heterogeneous, and there are few studies that integrate morbidity outcomes with objective measures of body composition using computed tomography (CT). The objective was to compare immunonutrition versus standard enteral supplementation in surgically treated patients with upper GI cancer (gastric, esophageal, pancreatic), evaluating postoperativecomplications and changes in body composition.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 110 (estimated)
- First submitted
- 13 Oct 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
- Diseases
- Pancreatic cancer
- NCT number
- NCT07884214
What you commit to
- Study type: Interventional
- Planned participants: 110
- From 1 Jan 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Emergency surgery
- Previous nutritional supplements
Other illness
- Non-surgical upper GI cancer
- End-stage liver o kidney disease
- Hypersensitivity to arginine, omega-3, or nucleotides
- HIV infection
- Active uncontrolled infection
- Dementia, advanced degenerative neurological disease.
Other
- Inability for oral nutrition (dysphagia, esophageal/pyloric stenosis)
- Pregnancy
- Intestinal obstruction
Who the study is looking for
- Patients eligible for upper GI cancer surgery
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Universitario Ramón y Cajal Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.