NCT07884903Not yet recruiting
Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks
A National Multicenter Prospective Cohort Study on the Incidence Characteristics and Risk Associations of Metabolic and Multi-system Comorbidities in Overweight and Obese Populations Stratified by Body Mass Index
Source: ClinicalTrials.gov · Last updated 21 Oct 2026
Brief summary (registry, in English)
This is a nationwide, multi-center, long-term follow-up study of overweight and obese adults in China. The study aims to recruit approximately 26,000 participants across 39 hospitals to better understand how body weight affects the development of obesity-related diseases over a 3-year period. Eligible participants are adults aged 18 to 79 years with a body mass index (BMI) of 23 kg/m² or higher. Participants will be grouped into four categories based on their BMI: overweight, mild obesity, moderate obesity, and severe obesity. At the beginning of the study, all participants will undergo a comprehensive health assessment, including physical measurements, body composition analysis, blood tests, and lifestyle questionnaires. Participants will then be followed for 3 years with annual check-ins to track any new health conditions. The main goal is to identify the 3-year risk of developing conditions such as type 2 diabetes, fatty liver disease, high blood pressure, and heart disease in different weight groups. This information will help doctors better predict and prevent obesity-related health problems in the future. Participation is voluntary, and all personal information will be kept confidential.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 25974 (estimated)
- First submitted
- 13 Oct 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 1 Jun 2028
- Lead sponsor
- Shanxi Bethune Hospital
- NCT number
- NCT07884903
What you commit to
- Study type: Observational
- Planned participants: 25974
- From 1 Nov 2026 to the primary completion date, 1 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent participation in other weight-loss or metabolic intervention trials
Other illness
- Secondary obesity (Cushing's syndrome, hypothyroidism, drug-induced or genetic obesity)
- End-stage severe chronic diseases (refractory heart failure, advanced malignancy, AIDS)
- Severe psychiatric disorders or cognitive impairment
Other
- Pregnancy or lactation
Who the study is looking for
- Adults aged 18 to 79 years
- BMI ≥23.0 kg/m² (overweight or obese per 2026 ADA criteria)
- Able to provide written informed consent
- Capable of completing baseline assessment and 3-year follow-up
- Local residency for ≥3 years
- Willing to provide fasting blood samples for storage
Age in the registry: 18 years to 79 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Endocrinology, Shanxi Bethune Hospital Coordinator of this site? Confirm its status | Taiyuan | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.