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NCT07887555Active, not recruiting

Integrated ¹⁸F-PSMA-1007 PET/MR Combined With Diffusion-Relaxation Correlation Spectrum Imaging for Preoperative Prediction of Postoperative Adverse Pathology and High ISUP Grade in Prostate Cancer

Source: ClinicalTrials.gov · Last updated 21 Oct 2026

Brief summary (registry, in English)

This retrospective observational study evaluates whether integrated ¹⁸F-PSMA-1007 PET/MR combined with diffusion-relaxation correlation spectrum imaging (DR-CSI) can help predict aggressive pathological features in patients with prostate cancer before radical prostatectomy. The study includes patients who underwent both ¹⁸F-PSMA-1007 PET/CT and PET/MR before surgery and had complete postoperative pathological information. Imaging features from PET/CT, conventional PET/MR, and DR-CSI are compared with clinical and pathological findings. The main aim is to determine whether PET/MR with DR-CSI can provide additional information for predicting adverse pathological findings after surgery and high postoperative ISUP grade. This study does not assign participants to any imaging examination or treatment. All analyses are based on previously collected clinical, imaging, and pathological data.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
300 (actual)
First submitted
12 Oct 2026
Start date
12 Oct 2026
Primary completion date
31 Dec 2027
Lead sponsor
Ruijin Hospital
NCT number
NCT07887555

What you commit to

  • Study type: Observational
  • Participants enrolled: 300
  • From 12 Oct 2026 to the primary completion date, 31 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous surgical treatment or hormonal therapy for prostate cancer.

Other illness

  • Diagnosis of another malignancy within the preceding 1 year or ongoing treatment for another malignancy.

Who the study is looking for

  • Adult patients aged \>30 years.
  • Newly diagnosed, biopsy-confirmed prostate cancer with planned radical prostatectomy.
  • Underwent both 18F-PSMA-1007 PET/MRI and PET/CT examinations.
  • Availability of pathological results from our institution or another hospital obtained within 3 months of the imaging examination.

Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Nuclear Medicine & Institute for medical imaging technology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,, Shanghai, shanghai Site
Coordinator of this site? Confirm its status
ShanghaiChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.