Evaluation of the Effect of a Low-FODMAP Diet on Gastrointestinal Symptoms and Inflammatory Markers in Fabry Patients

Brief summary (registry, in English)

The aim of this randomized controlled study is to evaluate the effects of a six-week low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet on gastrointestinal symptoms, inflammatory biomarkers, nutritional status, and quality of life in pediatric and adult patients with Fabry disease. A total of 30 patients with genetically or laboratory-confirmed Fabry disease are planned to be enrolled and randomly assigned to either an intervention group receiving an individualized low-FODMAP diet or a control group continuing their habitual diet. Assessments will be conducted at baseline and after six weeks. Gastrointestinal symptoms, stool characteristics, quality of life, anthropometric measurements, body composition, dietary intake, and biochemical parameters, including inflammatory biomarkers, will be evaluated. The study aims to investigate whether a low-FODMAP diet may provide additional benefits in managing gastrointestinal manifestations and inflammation in patients with Fabry disease.

What you commit to

• Study type: Interventional
• Planned participants: 30
• From 2 Jan 2026 to the primary completion date, 30 Jan 2027
• 1 site in 1 country
• Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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