NCT07892404Completed
Purse-String Versus Linear Closure After Ileostomy Reversal
Purse-String Versus Linear Closure With Drainage Access After Diverting Ileostomy Reversal in an Exploratory Randomized Comparison of Two Wound Management Protocols
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
This randomized study compared two wound closure and wound care protocols after reversal of a diverting ileostomy in adults previously treated surgically for rectal cancer. Participants were assigned to either purse-string skin closure with central drainage access or linear skin closure with marginal drainage access. Both protocols included temporary passive drainage and standardized postoperative wound irrigation. The study evaluated postoperative wound healing and wound-related outcomes during 30 days of follow-up. The hypothesis was that the purse-string protocol would be associated with fewer clinically important wound complications than the linear closure protocol.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 23 (actual)
- First submitted
- 17 Oct 2026
- Start date
- 10 Jun 2026
- Primary completion date
- 10 Aug 2026
- Lead sponsor
- Dnipro Regional Clinical Oncology Dispensary
- Diseases
- Colorectal cancer
- NCT number
- NCT07892404
What you commit to
- Study type: Interventional
- Participants enrolled: 23
- From 10 Jun 2026 to the primary completion date, 10 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active infection.
Other
- Planned ileostomy reversal outside the 35-40-day interval.
- Clinical or instrumental evidence of colorectal anastomotic leakage.
- Severe decompensated comorbidity.
- Refusal to participate.
Who the study is looking for
- Adults aged 18 years or older.
- History of low anterior resection for rectal cancer with creation of a diverting ileostomy.
- Planned ileostomy reversal 35-40 days after the primary operation.
- Colorectal anastomotic integrity and patency confirmed before reversal by contrast enema and rectosigmoidoscopy.
- Written informed consent to participate.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dnipro Regional Clinical Oncology Dispensary Coordinator of this site? Confirm its status | Dnipro | Ukraine | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.