NCT07893548Not yet recruiting
Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate
Anterior Bridge-Preserving Semi Circular Early Apical Release Versus Conventional Early Apical Release in Bipolar Prostate Enucleation: A Prospective Randomized Comparative Study
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation. Early apical release is a surgical step that frees the tip (apex) of the prostate at the start of the operation to reduce stretch on the urinary sphincter. The conventional technique cuts all the way around the apex, including the front (anterior) tissue next to the sphincter. This randomized trial compares a modified technique, Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), with conventional early apical release. ABP-S-EAR leaves the front tissue bridge between the 11 and 1 o'clock positions intact. Men aged 45 to 80 years scheduled for bipolar enucleation at Benha University Hospital, Egypt, will be randomly assigned to one technique. The main question is whether ABP-S-EAR improves urinary continence 1 month after surgery. The trial also compares patient-reported leakage, operative time, bleeding, catheter time, hospital stay, urinary symptoms, urine flow, and complications over 12 months.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 230 (estimated)
- First submitted
- 19 Oct 2026
- Start date
- 30 Nov 2026
- Primary completion date
- 30 May 2028
- Lead sponsor
- Benha University
- NCT number
- NCT07893548
What you commit to
- Study type: Interventional
- Planned participants: 230
- From 30 Nov 2026 to the primary completion date, 30 May 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous prostate, bladder neck, or urethral surgery that substantially alters apical anatomy.
- Urethral stricture or bladder neck sclerosis requiring concurrent intervention.
Other illness
- Neurogenic bladder dysfunction or major neurological disorder known to impair lower urinary tract function or continence.
- Untreated active urinary tract infection.
Who the study is looking for
- Men aged 45 to 80 years.
- Documented symptomatic benign prostatic obstruction (BPO) refractory to medical therapy or with BPO-related complications, with a clinical indication for endoscopic enucleation of the prostate.
- Able to understand the study procedures and give written informed consent.
Age in the registry: 45 years to 80 years · Sex: Male · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.