NCT07896174Recruiting
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
Effect of Preoperative Resistance and Aerobic Endurance Training on Surgical Outcomes and Evaluation of Patient Compliance With Prehabilitation in Colorectal Surgery: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions. The main questions it aims to answer are: * Does resistance (strength) training, aerobic (endurance) training, or a combination of both before surgery lower the rate and severity of complications in the first 30 days after surgery, compared with no exercise program? * Which factors influence how well patients follow a prehabilitation program, and does following the program affect surgical outcomes? Researchers will compare three exercise groups with a control group that receives standard care without an exercise program. Participants will: * Be randomly assigned to one of four groups: resistance training, aerobic training, combined training, or no exercise program (control) * Do the assigned home exercise program for 4 to 6 weeks before surgery, with weekly physiotherapy check-ups in person or by phone * Receive nutritional counseling, breathing exercises, and psychological support if needed, regardless of group * Keep a daily exercise diary and record their pulse daily * Undergo physical fitness tests (walking test, sit-to-stand test, handgrip strength) and quality-of-life questionnaires before surgery and 8 weeks after surgery
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 480 (estimated)
- First submitted
- 19 Oct 2026
- Start date
- 27 May 2026
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- Semmelweis University
- Diseases
- Colorectal cancer
- NCT number
- NCT07896174
What you commit to
- Study type: Interventional
- Planned participants: 480
- From 27 May 2026 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Unplanned acute surgery required during the prehabilitation period
- Transanal minimally invasive surgery (TAMIS)
- Palliative surgery only
Other
- Refusal to participate in the study
- Comorbidities precluding physical prehabilitation
- Physical, neurological or mental status precluding physical prehabilitation
- Pregnancy
- Preoperative preparation program deviating from the study protocol, as deemed necessary by the study team
Who the study is looking for
- Age over 18 years
- Elective, curative-intent colon or rectal resection
- Malignant or premalignant colorectal lesion
- Signed written informed consent after receiving study information
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Semmelweis University, Department of Surgery, Transplantation and Gastroenterology Coordinator of this site? Confirm its status | Budapest | Hungary | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.