NCT07896889Not yet recruiting
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
SCOPE-CT Pilot: Feasibility of Integrating ECG-Gated and Non-ECG-Gated Cardiac CT Angiography Into the Acute Stroke Imaging Workflow
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart. Standard emergency stroke imaging typically includes a CT scan of the head and CT angiography (CTA) of the head and neck, but does not routinely include imaging of the heart. This study will evaluate whether cardiac CT angiography (CTA) can be safely added to the standard acute stroke imaging workflow without delaying urgent stroke care. Participants with suspected acute ischemic stroke or high-risk transient ischemic attack (TIA) will undergo either prospective ECG-gated cardiac CTA or non-ECG-gated cardiac CTA during their acute stroke imaging examination. The primary goal of the study is to assess the feasibility of integrating cardiac CTA into routine stroke imaging by evaluating workflow impact, image quality, radiation exposure, contrast use, and protocol completion. Findings from this study may help improve the identification of cardiac sources of stroke and inform the design of future larger studies.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 19 Oct 2026
- Start date
- 26 Oct 2026
- Primary completion date
- 31 Oct 2027
- Lead sponsor
- Ottawa Hospital Research Institute
- Diseases
- Stroke
- NCT number
- NCT07896889
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 26 Oct 2026 to the primary completion date, 31 Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior enrollment in the study.
Other illness
- Severe renal impairment where additional contrast is deemed clinically inappropriate.
- The treating stroke/radiology team determines that additional cardiac CTA is not appropriate.
Other
- Known contraindication to iodinated contrast.
- Hemodynamic instability precluding additional imaging.
- Pregnancy.
- Severe motion/agitation where imaging is not feasible.
Who the study is looking for
- Adult patients presenting with suspected acute ischemic stroke or TIA who undergo standard acute stroke CT/CTA imaging.
- Age ≥18 years.
- Suspected acute ischemic stroke or high-risk TIA.
- Undergoing standard-of-care acute stroke CT/CTA.
- Presentation within a clinically relevant acute stroke imaging window, ≤24 hours from last-known-well.
- Able to undergo iodinated contrast-enhanced CTA
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Ottawa Hospital Coordinator of this site? Confirm its status | Ottawa | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.