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NCT07897669Not yet recruiting

A Real-world Study to Learn About of the Characteristics and Outcomes of Advanced or Metastatic Bladder Cancer Patients With Different Histologies

CHARACTERISTICS AND OUTCOMES AMONG PATIENTS WITH DIFFERENT PREDOMINANT VARIANT HISTOLOGY TYPES OF LOCALLY ADVANCED OR METASTATIC BLADDER CARCINOMA (LA/MBC): A FLATIRON HEALTH REAL-WORLD STUDY

Source: ClinicalTrials.gov · Last updated 27 Oct 2026

Brief summary (registry, in English)

Bladder cancer (urothelial carcinoma) is a disease where cells in the bladder grow out of control. The bladder is an organ in the lower part of the body that stores urine. When someone has bladder cancer, abnormal cells form in the bladder and can spread to other parts of the body if not treated. Bladder cancer that has spread outside the bladder is called advanced or metastatic bladder cancer. When cancer develops, a pathologist examines a sample of the tumour under a microscope to see which cells the cancer started from. This is called the cancer's histology. Most bladder cancers begin in the cells that line the inside of the bladder and are called urothelial cancers. Less commonly, bladder cancer can develop from other cell types. The purpose of this study is to examine the types of histology that adults with advanced or metastatic bladder cancer have. The researchers will also describe the demographics (information such as age, sex and race) clinical characteristics and outcomes of those patients. This is a real-world study, not a clinical study. This means that researchers will look at what happens when patients receive the treatments prescribed by their own doctor as part of their usual healthcare treatment. In this study, researchers will use information from cancer clinics (Flatiron Health electronic health records). to assess information for each participant for at least 6 months. The study will include patients' information from the database who: * Were identified to have advanced or metastatic bladder cancer. * Started their first treatment after 01 Apr 2023. * Were 18 years of age or older when they were diagnosed with advanced disease.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
5122 (estimated)
First submitted
20 Oct 2026
Start date
Oct 2026
Primary completion date
Apr 2027
Lead sponsor
Pfizer
NCT number
NCT07897669

What you commit to

  • Study type: Observational
  • Planned participants: 5122
  • From Oct 2026 to the primary completion date, Apr 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Primary site of disease other than bladder, renal pelvis, ureter, or urethra

Other

  • Clinical trial participation

Who the study is looking for

  • Adults (18 years or older) diagnosed with locally advanced or metastatic bladder cancer (la/mBC) in the Flatiron Health database.
  • Started first line systemic treatment for la/mBC during the study period.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.