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NCT07901335Recruiting

KLF4 Epigenetic Modulation

KLF4 Epigenetic Modulation During Polyps-adenoma Progression

Source: ClinicalTrials.gov · Last updated 28 Oct 2026

Brief summary (registry, in English)

The study investigates the epigenetic regulation of KLF4 during the progression from colorectal polyps to adenomas and carcinomas. Quantitative KLF4 methylation will be assessed in colorectal tissue samples obtained during routine colonoscopy, together with KLF4 gene expression and its correlation with methylation status in matched tissue samples. The study will also evaluate quantitative and site-specific molecular approaches for the assessment of KLF4 methylation.

Status (registry)
Recruiting
Study type
Observational
Enrollment
170 (estimated)
First submitted
22 Oct 2026
Start date
1 Oct 2026
Primary completion date
31 Jul 2027
Lead sponsor
Azienda USL Reggio Emilia - IRCCS
NCT number
NCT07901335

What you commit to

  • Study type: Observational
  • Planned participants: 170
  • From 1 Oct 2026 to the primary completion date, 31 Jul 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Concomitant diagnosis of colorectal carcinoma

Who the study is looking for

  • Patients undergoing routine colonoscopy
  • \> 18 years of age
  • Diagnosed by S.C. Anatomia Patologica, AUSL-IRCCS Reggio Emilia

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Azienda USL IRCCS di Reggio Emilia
Coordinator of this site? Confirm its status
Reggio EmiliaItalyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.