NCT07901335Recruiting
KLF4 Epigenetic Modulation
KLF4 Epigenetic Modulation During Polyps-adenoma Progression
Source: ClinicalTrials.gov · Last updated 28 Oct 2026
Brief summary (registry, in English)
The study investigates the epigenetic regulation of KLF4 during the progression from colorectal polyps to adenomas and carcinomas. Quantitative KLF4 methylation will be assessed in colorectal tissue samples obtained during routine colonoscopy, together with KLF4 gene expression and its correlation with methylation status in matched tissue samples. The study will also evaluate quantitative and site-specific molecular approaches for the assessment of KLF4 methylation.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 170 (estimated)
- First submitted
- 22 Oct 2026
- Start date
- 1 Oct 2026
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- Azienda USL Reggio Emilia - IRCCS
- Diseases
- Colorectal cancer
- NCT number
- NCT07901335
What you commit to
- Study type: Observational
- Planned participants: 170
- From 1 Oct 2026 to the primary completion date, 31 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant diagnosis of colorectal carcinoma
Who the study is looking for
- Patients undergoing routine colonoscopy
- \> 18 years of age
- Diagnosed by S.C. Anatomia Patologica, AUSL-IRCCS Reggio Emilia
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Azienda USL IRCCS di Reggio Emilia Coordinator of this site? Confirm its status | Reggio Emilia | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.