NCT07901621Not yet recruiting
Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b
Effects of Combined and Multicomponent Training on Physiological, Functional, and Quality of Life Parameters in People With Chronic Kidney Disease: A Randomized Controlled Clinical Trial
Source: ClinicalTrials.gov · Last updated 30 Oct 2026
Brief summary (registry, in English)
This randomized controlled trial will compare the effects of 12 weeks of combined training (aerobic plus resistance exercise) and multicomponent training (aerobic plus resistance plus balance exercise) with a control group without supervised exercise in adults aged 55 to 70 years with chronic kidney disease (CKD) stages 3a or 3b who are not on dialysis. Fifty-seven participants will be randomly allocated (1:1:1) to one of the three groups. Supervised training sessions will last 60 minutes and will be held three times a week at the University of Brasilia, Brazil. The main questions are whether these programs improve peak oxygen uptake, resting blood pressure, physical health-related quality of life, and estimated glomerular filtration rate, and whether adding balance exercises provides additional benefits for balance, falls, and functional capacity.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 57 (estimated)
- First submitted
- 21 Oct 2026
- Start date
- May 2027
- Primary completion date
- Nov 2027
- Lead sponsor
- University of Brasilia
- Diseases
- Chronic kidney disease
- NCT number
- NCT07901621
What you commit to
- Study type: Interventional
- Planned participants: 57
- From May 2027 to the primary completion date, Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- CKD stages 1, 2, 4, or 5, dialysis, or kidney transplantation
- Concurrent participation in another supervised exercise program
Other illness
- Polycystic kidney disease
- Congestive heart failure, advanced chronic obstructive pulmonary disease, heart disease, arrhythmias, unstable angina, or type 1 diabetes mellitus
- Dementia or psychiatric disorders that compromise understanding of instructions or safe exercise
- Musculoskeletal injuries or neurological disorders that prevent participation in the exercise program
Who the study is looking for
- CKD stage 3a or 3b (eGFR 30-59 mL/min/1.73 m2) according to KDIGO 2024, diagnosed at least 6 months before enrollment
- Age between 55 and 70 years
- Body mass index between 18.5 and 35 kg/m2
- No participation in a structured exercise program in the previous 3 months
- Controlled systemic arterial hypertension and/or type 2 diabetes mellitus are allowed
- No clinical contraindication to exercise training or to the study assessments
- Literacy sufficient to understand the informed consent form and questionnaires
Age in the registry: 55 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Brasilia - Faculty of Physical Education and Olympic Center Coordinator of this site? Confirm its status | Brasília | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.