NCT07902739Completed
Pulsed Field Ablation of Atrial Fibrillation: CENTAURI Versus FARAPULSE
Prospective Randomized Clinical Comparison of Catheter Ablation of Atrial Fibrillation Using the CENTAURI PEF System and the FARAPULSE System
Source: ClinicalTrials.gov · Last updated 29 Oct 2026
Brief summary (registry, in English)
The aim of this study is to compare the efficacy of two commercially available pulsed field ablation (PFA) systems for catheter ablation of atrial fibrillation. Patients are randomized 1:1 to point-by-point PFA using the CENTAURI PEF system with 3D electroanatomical mapping, or to single-shot PFA using the FARAPULSE pentaspline catheter guided by fluoroscopy and intracardiac echocardiography. The primary endpoint is freedom from documented atrial arrhythmia recurrence between 3 and 12 months after ablation.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 325 (actual)
- First submitted
- 21 Oct 2026
- Start date
- 17 May 2024
- Primary completion date
- 5 Oct 2026
- Lead sponsor
- St. Anne's University Hospital Brno, Czech Republic
- Diseases
- Atrial fibrillation
- NCT number
- NCT07902739
What you commit to
- Study type: Interventional
- Participants enrolled: 325
- From 17 May 2024 to the primary completion date, 5 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \-
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Anne's University Hospital Brno Coordinator of this site? Confirm its status | Brno | Czechia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.