NCT07903792Recruiting
Diagnostic Value of Oropharyngeal Suction and Effect of Respiratory Physiotherapy on the Detection of Microorganisms in the Pediatric Patient
Diagnostic Value of Oropharyngeal Suction Compared With Induced Sputum and Oropharyngeal Swab, and the Effect of Respiratory Physiotherapy on the Detection of Microorganisms in Paediatric Patients With Chronic Respiratory Disease: a Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 29 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to determine the effectiveness of oropharyngeal suction in detecting microorganisms by comparing it with induced sputum and oropharyngeal swab samples. It also aims to assess the effect of respiratory physiotherapy on improving the results obtained in children aged 5-18 years with chronic lung disease. The main questions it aims to answer are: * What is the diagnostic efficacy of oropharyngeal suction in detecting microorganisms compared with induced sputum? * What is the effect of undergoing a physiotherapy session before sample collection? * How do the results obtained from oropharyngeal suction correlate with those obtained from oropharyngeal swabs? * How does the age of the participants affect the results obtained from each sampling technique and the effect of prior physiotherapy? * Are these techniques safe? Researchers will compare samples collected after a physiotherapy session with those collected without prior physiotherapy to determine whether physiotherapy improves culture results. Participants will be randomized into two groups: one group will undergo a physiotherapy session before sample collection, while the other will not. Three samples will be collected from each participant using oropharyngeal suction, an oropharyngeal swab, and induced sputum. Each participant may take part on multiple occasions, provided that at least one month has elapsed since their previous participation. On each occasion, participants will be randomized again.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 196 (estimated)
- First submitted
- 12 Aug 2026
- Start date
- 1 Jun 2026
- Primary completion date
- Jun 2028
- Lead sponsor
- Corporacion Parc Tauli
- Diseases
- Cystic fibrosis
- NCT number
- NCT07903792
What you commit to
- Study type: Interventional
- Planned participants: 196
- From 1 Jun 2026 to the primary completion date, Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having taken antibiotics in the previous week, except for patients receiving chronic azithromycin treatment.
Other illness
- Severe acute infection that contraindicates any of the procedures (e.g., severe respiratory failure, shock, etc.).
- Decompensated cardiorespiratory disease.
- History of severe adverse reactions to hypertonic saline nebulization.
Other
- Patients who do not consent to or are unable to undergo the procedures.
Who the study is looking for
- Having a chronic respiratory disease that requires sputum sample collection.
- Being able to cooperate during the physiotherapy session.
- Having provided signed informed consent.
Age in the registry: 5 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Corporacio Sanitaria Parc Tauli Coordinator of this site? Confirm its status | Sabadell | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.