NCT07904260Not yet recruiting
Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions
Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions: a Multicenter Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 29 Oct 2026
Brief summary (registry, in English)
Patients living in high-altitude areas naturally have lower blood oxygen levels. Those at high risk for Obstructive Sleep Apnea (OSA) face an even greater risk of low oxygen during painless gastrointestinal endoscopy. This multicenter study will randomly assign these patients to receive either High-Flow Nasal Oxygen (HFNC) or standard oxygen therapy during their procedure, aiming to find out if HFNC can safely and effectively reduce the risk of low oxygen events.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 430 (estimated)
- First submitted
- 24 Oct 2026
- Start date
- 2 Nov 2026
- Primary completion date
- 31 Oct 2027
- Lead sponsor
- Diansan Su
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT07904260
What you commit to
- Study type: Interventional
- Planned participants: 430
- From 2 Nov 2026 to the primary completion date, 31 Oct 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with absolute contraindications to high-flow nasal oxygen therapy, including confirmed complete upper airway obstruction, skull base fracture, nasal bone fracture, pneumothorax, or pneumomediastinum.
- Prior tracheostomy.
Other illness
- Allergy to sedatives such as propofol.
Other
- ASA physical status \> IV.
- Planned endotracheal intubation.
- Confirmed pregnancy or current breastfeeding.
- Current participation in another clinical trial.
- Patients deemed unsuitable for this trial by the investigator.
Who the study is looking for
- Age ≥18 years.
- Long-term residence in a high-altitude region (continuous residence in a high-altitude region within the past 1 year).
- STOP-Bang score ≥5.
- Scheduled for sedated gastrointestinal endoscopy (gastroscopy, colonoscopy, or combined gastroscopy + colonoscopy).
- Patients have signed the informed consent form.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital Zhejiang University School of Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
| Haiyan County People's Hospital Coordinator of this site? Confirm its status | Sanjiaocheng | China | Unknown status |
| Qinghai Provincial Traffic Hospital Coordinator of this site? Confirm its status | Xining | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.