NCT07906821Recruiting
Ultrasound-guided Microwave Ablation of Benign Thyroid Nodules
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if microwave ablation of benign thyroid nodules under local anaesthesia is a safe and effective procedure compared to open thyroidectomy. The main questions it aims to answer are: Dose microwave Ablation effectively cause shrinkage of thyroid nodules? Can ablation of selective area of nodules be safely performed under ultrasound guidance, avoiding critical structures including recurrent laryngeal nerve, major vessels and trachea? Researchers will recruit subjects with symptomatic benign thyroid nodules for Microwave Ablation. Participants will: Undergo ultrasound guided Microwave Ablation of benign thyroid nodules. Visit the clinic at post operation 2-week, 3-month, 6-month, 12-month, 2-year and 3-year for checkups and tests. Fill in questionnaire at each clinic visit for pain, pressure symptoms, cosmetic overall satisfaction in Visual Analog Scale.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 26 Oct 2026
- Start date
- 31 Aug 2023
- Primary completion date
- 31 May 2029
- Lead sponsor
- Chinese University of Hong Kong
- NCT number
- NCT07906821
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 31 Aug 2023 to the primary completion date, 31 May 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous anterior neck surgery
- Previous radiotherapy at the head and neck region
- Severe concomitant illness that drastically shortens life expectancy or increases risk of therapeutic intervention
Other illness
- Malignant thyroid nodule
- Presence of another malignancy, lateral neck, or distant metastasis
- Cervical spine disease precluding extension of the neck
- Vulnerable population (e.g. Cognitive impairment, pregnancy)
Age
- Patients under 18 years old
Other
- Asymptomatic thyroid nodule
- High risk USG features or cytological features
- Obesity with BMI \> 35kg/m2
- Non-correctable coagulopathy
Who the study is looking for
- Thyroid nodules or dominant nodule of multinodular goitre
- Symptomatic thyroid nodule not less than 2cm
- Benign thyroid nodule confirmed by Fine needle aspiration for cytology (FNAC)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Chines University of Hong Kong Coordinator of this site? Confirm its status | Shatin | Hong Kong | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.