NCT07908628Not yet recruiting
Effectiveness of Internet-based Unified Protocol (iUP) for Emotional Problems: A Randomized Controlled Trial
Effectiveness of an Adapted, Internet-based Version of a Transdiagnostic Intervention (Unified Protocol) for Emotional Problems: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if an internet-based Unified Protocol (iUP) intervention is effective for treating depression and anxiety disorders in Hong Kong young adults aged 18-29 years. This study is conducted within the eClinic, a public mental health support service provided by a Hong Kong non-government organisation (NGO). The main questions it aims to answer are: * Is the iUP intervention effective in treating depression and anxiety disorders? * How long is the treatment effect sustained after the intervention ends? * Does the intervention also improve real-world functioning, such as occupational and academic performance? Researchers will compare participants who receive the iUP intervention immediately with those in a wait-list control group (who receive no intervention during the waiting period) to evaluate the effectiveness of iUP. Participants will: * Receive a 14-week iUP intervention either immediately or after a 14-week waiting period according to randomisation * Complete weekly and follow-up questionnaires throughout the study period
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 78 (estimated)
- First submitted
- 26 Oct 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 31 Oct 2036
- Lead sponsor
- New Life Psychiatric Rehabilitation Association
- Diseases
- Depression
- NCT number
- NCT07908628
What you commit to
- Study type: Interventional
- Planned participants: 78
- From 1 Nov 2026 to the primary completion date, 31 Oct 2036
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Present with a history of psychosis in the recent 2 years
- Demonstrate sub-average intelligence (e.g., based on a history of intellectual disability)
- Present with a known, formal diagnosis of autism spectrum disorder (ASD)
- Present with unstable psychiatric medication states in recent 3 months (i.e., had recent initiation of psychiatric medication or dosage change)
Other
- Present with severe risk for self-harm or suicide (i.e., indicated as being at higher risk on the P4 Screener)
- Present with active homicidal ideations
- Concurrently receive other psychological services
- Present with current substance abuse
Who the study is looking for
- Able to speak, read and write Chinese
- Present caseness according to NHS Talking Therapies (formerly IAPT) criteria, defined as a PHQ-9 total score ≥ 10 and/or a GAD-7 total score ≥ 8 at the start of treatment
Age in the registry: 18 years to 29 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| New Life Psychiatric Rehabilitation Association Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.