NCT07909772Completed
Effects of a Multispecies Probiotic on Metabolic, Liver, and Gut Health
Effects of a Multispecies Probiotic on Metabolic Biomarkers, Liver Health, Inflammation, Gut Microbiota, and Gastrointestinal Symptoms: A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 3 Nov 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if multistrain probiotic works to improve severe metabolic markers and gastrointestinal symptoms in obese MASLD patients. The main questions it aims to answer are Does this multistrain probiotic improve the composition of gut microbiota? Does it improve gastrointestinal symptoms and metablic profiles? Does it help in improving the grade of liver steatosis, and lose weight? Researchers will compare a multistrain probiotic group to a control group. Participants will: The probiotic group will take multistrain probiotics daily for 6 months in addition to a dietary plan and physical activity recommendations. The control group will only follow a dietary plan and physical activity recommendations Visit the clinic every 3 months for checkups and be called every month for regular follow-ups
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 56 (actual)
- First submitted
- 14 Oct 2026
- Start date
- 1 Mar 2025
- Primary completion date
- 30 Jul 2026
- Lead sponsor
- University of Bari
- Diseases
- Obesity
- NCT number
- NCT07909772
What you commit to
- Study type: Interventional
- Participants enrolled: 56
- From 1 Mar 2025 to the primary completion date, 30 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- suffering from severe cardiovascular, renal, or hepatic medical conditions.
Other
- patients who were already on antibiotic treatment or had been taking probiotics within the last three months
- pregnant or lactating women,
Who the study is looking for
- All patients were either diagnosed with MASLD,
- had a body mass index of 25 kg/m² or more
- had gastrointestinal symptoms,
- had not taken antibiotics or probiotics for the last three months
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Biomedical Sciences and Human Oncology - Clinica medica "A. Murri" Coordinator of this site? Confirm its status | Bari | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.