The Impact of Osteosarcopenia on Falls, Kinesiophobia, and Quality of Life in Postmenopausal Women

Brief summary (registry, in English)

Osteosarcopenia (OSP) is defined as the coexistence of sarcopenia and osteoporosis/osteopenia. There is an intense and complex interaction-both mechanical (the "mechanostat" hypothesis) and biochemical (involving factors such as estrogen, testosterone, GH, IGF-1, IL-6, and osteocalcin)-between osteoporosis and sarcopenia. The general consensus is that sarcopenia leads to a reduction in bone mineral density. OSP is associated with significant physical disability, which poses a major threat to the future loss of independence. The increased propensity for falls-a consequence of sarcopenia-compounds the risk of fractures associated with osteoporosis, further exacerbating adverse health outcomes. Kinesiophobia, or the "fear of movement," is an excessive and irrational dread of performing physical movements or activities, stemming from the fear of a painful injury or the possibility of re-injury; this often leads to restrictions in activities of daily living. In a clinical setting, kinesiophobia is a critical issue that must be addressed to effectively manage a patient's disability, as it directly influences rehabilitation strategies. While there is some limited literature exploring the individual associations of osteoporosis and sarcopenia with kinesiophobia, no research has yet examined the relationship between osteosarcopenia and kinesiophobia. Our study aims to determine the impact of osteosarcopenia on kinesiophobia and quality of life in postmenopausal women.

What you commit to

• Study type: Observational
• Participants enrolled: 109
• From 2 Jan 2025 to the primary completion date, 10 Nov 2026
• 1 site in 1 country
• Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

Age in the registry: 45 years to 75 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

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