NCT07911033Not yet recruiting
Relationship Between Insulin Dose and Complications in Type 1 Diabetes
Insulin Dose and Vascular Complications in Type 1 Diabetes: Its Role Beyond Insulin Resistance and Glycemia
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
The goal of this observational study is to better understand how the amount of insulin people with type 1 diabetes are using relates to blood glucose control and the risk of complications. The main questions this study aims to answer are: 1) Is insulin dose related to the long-term risk of developing heart disease, kidney disease and other complications in people with type 1 diabetes, after accounting for blood glucose? and 2) Does insulin dose relate to early signs of heart and kidney disease (i.e., disease that is not clinically detectable) in people with type 1 diabetes who are using modern diabetes management regimens?
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 22 Oct 2026
- Start date
- Jan 2027
- Primary completion date
- Dec 2028
- Lead sponsor
- Rachel Miller
- Diseases
- Type 1 diabetes
- NCT number
- NCT07911033
What you commit to
- Study type: Observational
- Planned participants: 80
- From Jan 2027 to the primary completion date, Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Study Aim 2 - History of major cardiovascular disease, kidney failure, or pancreatic transplant
Other
- Study Aim 1 - For each outcome of interest, individuals who already had the outcome at study baseline.
Who the study is looking for
- Study Aim 1 - All existing participants of the Pittsburgh EDC study
- Study Aim 2 - Existing participants of the Pittsburgh EDC study who were alive and not withdrawn as of the most recent (2023-24) survey follow-up
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.