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NCT07911878Recruiting

Development, Validation and Normative Data of the Italian Battery for the Recognition of Famous Faces (FAME)

Sviluppo, Validazione e Dati Normativi Della Batteria Italiana Per il Riconoscimento Dei Volti Famosi I-FACE

Source: ClinicalTrials.gov · Last updated 3 Nov 2026

Brief summary (registry, in English)

The I-FACE project aims to develop and validate a battery to assess famous-face recognition in people with neurodegenerative diseases and stroke. It will examine face naming, familiarity, and semantic knowledge, establish norms for the Italian population, and test how well the measures identify recognition difficulties in patients with frontotemporal dementia, Alzheimer's disease, and stroke.

Status (registry)
Recruiting
Study type
Observational
Enrollment
300 (estimated)
First submitted
23 Oct 2026
Start date
5 Sept 2025
Primary completion date
31 Jan 2028
Lead sponsor
Istituti Clinici Scientifici Maugeri SpA
NCT number
NCT07911878

What you commit to

  • Study type: Observational
  • Planned participants: 300
  • From 5 Sept 2025 to the primary completion date, 31 Jan 2028
  • 10 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • History of previous stroke or multifocal stroke documented by imaging. Brainstem or cerebellar stroke. History of traumatic brain injury (TBI), seizures, brain tumors, neurodegenerative diseases, or psychiatric disorders.

Other illness

  • Uncorrected vision or hearing impairment.
  • Frontotemporal Dementia (FTD) Patients
  • History of neurological diseases other than FTD (e.g., stroke, brain tumor, multiple sclerosis, traumatic brain injury).
  • Uncorrected vision or hearing impairment. History of serious psychiatric diseases, developmental disorders (e.g., autism spectrum), or intellectual disability.
  • Dementia severity (CDR) \> 1.
  • Alzheimer's Disease (AD) Patients
  • History of neurological diseases other than AD (e.g., stroke, brain tumor, multiple sclerosis, traumatic brain injury).
  • Uncorrected vision or hearing impairment. History of serious psychiatric diseases, developmental disorders, or intellectual disability.
  • Dementia severity (CDR) \> 1.
  • Post-Stroke Patients

Who the study is looking for

  • Age 40-85 years. No chronic medical, neurological, or psychiatric conditions, or major depressive episode detected during screening.
  • No history of schizophrenia or bipolar disorder in the 5 years prior to screening.
  • Mini-Mental State Examination (MMSE) score ≥ 26.
  • Diagnosis of probable FTD according to established clinical criteria. Age 40-85 years. Ability to provide informed consent.
  • Diagnosis of probable AD according to established clinical criteria. Age 40-85 years. Ability to provide informed consent.
  • Subacute phase: 1 week to 3 months post-event. Ischemic or hemorrhagic stroke confirmed by neuroimaging and/or clinical judgment.

Criteria the registry did not label

  • Healthy Controls (HC)

Age in the registry: 40 years to 85 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (10)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Istituti Clinici Scientifici Maugeri IRCCS Bari
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BariItalyRecruiting
IRCCS Maugeri Castel Goffredo
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Castel GoffredoItalyNot yet recruiting
IRCCS Maugeri Lumezzane
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LumezzaneItalyRecruiting
Istituti Clinici Scientifici Maugeri IRCCS, Milano
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MilanItalyRecruiting
ICS Maugeri - Mistretta
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MistrettaItalyRecruiting
IRCCS Maugeri Montescano
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MontescanoItalyRecruiting
IRCCS Maugeri Pavia
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PaviaItalyRecruiting
ICS Maugeri Sciacca
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SciaccaItalyRecruiting
IRCCS Maugeri Telese Terme
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Telese TermeItalyRecruiting
IRCCS Maugeri Veruno
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VerunoItalyNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.