NCT07915934Not yet recruiting
Adapting the "Do More, Feel Better" Intervention for Older People Living With HIV
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
More than half of people living with HIV (PWH) in the United States are 50 years of age or older. Older PWH have a 2.3-fold increased risk of depression compared to their peers without HIV. The investigator team has developed a streamlined lay-delivered behavioral activation intervention called "Do More, Feel Better" that has been shown to decrease depressive symptoms among older adults obtaining services in community senior centers. The investigators propose to (1) identify barriers and facilitators to improving mental health among older PWH by using this intervention in the context of Ryan White case management services, (2) adapt and enhance the intervention to meet the needs of older PWH, and (3) conduct a pilot randomized controlled trial to determine the acceptability, feasibility, and appropriateness of the adapted DMFB intervention.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- First submitted
- 20 Oct 2026
- Start date
- 8 Nov 2027
- Primary completion date
- 26 Jun 2028
- Lead sponsor
- University of Washington
- Diseases
- HIV
- NCT number
- NCT07915934
What you commit to
- Study type: Interventional
- Planned participants: 48
- From 8 Nov 2027 to the primary completion date, 26 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- a diagnosis of bipolar disorder, schizophrenia or psychosis
- dementia or Telephone Interview for Cognitive Status-modified (TICS-M) scores \<21
Other
- active suicidal ideation
- current regular psychotherapy
- antidepressant use, unless at stable doses for 12 weeks
Who the study is looking for
- ≥50 years of age
- living with HIV
- English-speaking
- elevated depressive symptoms (PHQ-9 ≥10)
- resident in Washington for ≥1 year
- assigned to a Ryan White case manager
- willing to undergo all study procedures
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Washington Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.