NCT07919457RecruitingPhase 2
Phenotype-based Model for Managing Chronic Post-treatment Pain Among Head and Neck Cancer Survivors: a Pilot Study
Source: ClinicalTrials.gov · Last updated 5 Nov 2026
Brief summary (registry, in English)
The goal of this clinical trial is to find out whether a phenotype-based pain management approach can reduce chronic pain in adults (18 years and older) who have completed curative treatment for head and neck cancer and continue to experience chronic post-treatment pain. The main questions it aims to answer are: * Does a phenotype-based pain management approach reduce participants' average pain by at least 75% after one month of treatment? * Is the treatment safe, with 10% or fewer participants stopping treatment because of side effects? Participants will: * Attend three study visits over one month (at baseline, 2 weeks, and 4 weeks). * Complete questionnaires about their pain, anxiety, depression, medication side effects, and use of pain medicines. * Undergo a detailed examination to identify the type (phenotype) of their pain. * Receive a treatment plan tailored to their pain phenotype, which may include medications, trigger point injections, or nerve blocks, depending on their symptoms and pain severity. * Return for follow-up visits to assess pain relief, medication side effects, and use of breakthrough pain medication.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 1 Nov 2026
- Start date
- 16 Jul 2026
- Primary completion date
- 31 Jan 2027
- Lead sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
- Diseases
- Head and neck cancer
- NCT number
- NCT07919457
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 40
- From 16 Jul 2026 to the primary completion date, 31 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgical wound dehiscence
Other illness
- Active disease recurrence or metastasis
- Persistent mucositis, oral infection, or hardware failure at the treatment site
- Cognitive impairment that limits the ability to complete study questionnaires
Who the study is looking for
- Adults (≥18 years) with history of curative treatment for head and neck cancer
- Chronic post-treatment pain disorder
- Absence of clinical and radiological evidence of recurrent disease
- Ability to provide informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shaukat Khanum Memorial Cancer Hospital & Research Centre | Lahore | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.