NCT07922317Recruiting
ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
Evaluation of Clinical Outcomes Following Endovascular Thrombectomy for Acute Ischemic Stroke With Anterior Large Vessel Occlusion in Extended Time Window (24-72 Hours)
Source: ClinicalTrials.gov · Last updated 6 Nov 2026
Brief summary (registry, in English)
The ELATE study is a prospective, observational study designed to evaluate the clinical outcomes and safety profile of endovascular thrombectomy compared with best medical treatment alone in patients presenting with acute ischemic stroke due to anterior large vessel occlusion within 24 to 72 hours from stroke onset or last known well.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 284 (estimated)
- First submitted
- 2 Nov 2026
- Start date
- 6 Jul 2026
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- 115 People's Hospital
- Diseases
- Stroke
- NCT number
- NCT07922317
What you commit to
- Study type: Observational
- Planned participants: 284
- From 6 Jul 2026 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pre-stroke modified Rankin Score (mRS) score of >2 (indicating previous disability)
Other illness
- Intracranial hemorrhage identified by CT or MRI
- Any terminal illness such that the patient has a life expectance of less than 1 year.
- Patients with active cancer and undergoing treatment for cancer are excluded
Other
- Pregnancy
Who the study is looking for
- Age ≥ 18 years
- Presentation with acute ischemic stroke within 24 to 72 hours of stroke onset or last known well.
- Baseline NIHSS ≥ 8 (If patients have NIHSS < 8 at admission and experienced END to an NIHSS score ≥ 8 or higher, they also were included if they were 24 to 72 hours from the LKW at this point)
- Clinical diagnosis of AIS due to anterior circulation LVO (internal carotid artery (ICA) extracranial or intracranial segment, middle cerebral artery (MCA) M1 and proximal M2 segment) on brain imaging (CTA/MRA).
- Imaging criteria: must fulfill at least one:
- 1) Core-penumbra mismatch on CT perfusion (CTP) or MR perfusion (MRP) assessed: infarct core volume ≤ 70mL, mismatch ratio ≥ 1,8 and mismatch volume ≥ 15mL.
- 2) ASPECTS ≥6 on non-contrast CT or diffusion-weighted imaging (DWI).
- Written informed consent (by patient or proxy, according to local requirements)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 115 PEOPLE's HOSPITAL Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.