NCT07922850Not yet recruiting
Tailored Nutrition vs. Exercise Prehabilitation Before Colorectal Cancer Surgery
ColoREctal Cancer Surgery and Multimodal pREhabilitation Assessing Tailored Nutrition vs. Exercise - An Open Label Superiority Multicenter Randomized Controlled Trial.
Source: ClinicalTrials.gov · Last updated 6 Nov 2026
Brief summary (registry, in English)
This study will test whether tailored nutritional support before surgery, alone or combined with a structured exercise program, can help adult patients recover better after surgery for colorectal (bowel) cancer. Participants will be randomly assigned to one of three groups: usual care, tailored nutritional support alone, or nutritional support combined with a structured exercise program (multimodal prehabilitation). The main goal is to find out whether either approach improves physical function 30 days after surgery, measured by how far participants can walk in 6 minutes (the 6-minute walk test). The study will also look at nutritional intake, physical function, quality of life, complications, hospital readmissions, and length of hospital stay. A total of 140 adult patients scheduled for surgery for colorectal cancer at hospitals in Northern Norway will be enrolled.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 140 (estimated)
- First submitted
- 2 Nov 2026
- Start date
- 1 Dec 2026
- Primary completion date
- Aug 2028
- Lead sponsor
- University Hospital of North Norway
- Diseases
- Colorectal cancer
- NCT number
- NCT07922850
What you commit to
- Study type: Interventional
- Planned participants: 140
- From 1 Dec 2026 to the primary completion date, Aug 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
AI-kivonat: who the study is looking for
Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults planning to have colorectal (bowel) cancer surgery. It tests nutrition support, alone or with exercise, before surgery.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Colorectal cancer with planned elective (non-emergency) surgery. No known metastatic disease.
- Earlier treatment
- If neoadjuvant treatment (given before surgery) was given, it must be finished. No earlier structured multimodal prehabilitation in this cancer pathway.
Main reasons for not taking part
- Known metastatic disease
- Cannot walk for six minutes or rise from a chair alone
- Planned multivisceral resection or complex reconstruction for locally advanced cancer
- Severe renal failure, including dialysis
- Cannot use the telemedicine technology needed for follow-up, if telemedicine follow-up is planned
Read by machine on 9 Nov 2026.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous participation in structured multimodal prehabilitation as part of the current cancer treatment pathway before inclusion, for example during neoadjuvant therapy
- Previous major gastrointestinal surgery considered by the treating clinician to substantially affect the planned colorectal cancer surgery or postoperative recovery
- No permanent address or expected hospital/institutional stay for more than 50% of the time between diagnosis and planned surgery
Other illness
- Known metastatic disease
- Physical impairment that prevents the participant from walking for six minutes or rising independently from a chair
- Planned multivisceral resection and/or complex reconstruction due to locally advanced cancer
- Cognitive impairment that prevents the participant from understanding the intervention, exercise programme, questionnaires, or written and oral instructions
- Severe comorbidity or other medical condition that, in the judgement of the treating clinician, precludes participation in structured exercise
- Severe renal failure, including patients requiring dialysis or with clinically significant electrolyte disturbances
Other
- Ongoing severe nutritional support, such as parenteral nutrition, that limits the feasibility of the allocated intervention
- Inability to use the telemedicine technology required for follow-up when telemedicine-based follow-up is planned
Who the study is looking for
- Patients undergoing elective colorectal cancer surgery who give informed consent and meet all of the following will be eligible:
- Planned elective surgery for colorectal cancer
- Age >=18 years
- If neoadjuvant treatment has been given, treatment must be completed and the patient must be scheduled for surgery
- Able to understand Norwegian sufficiently to receive study information, complete questionnaires, and follow written and oral instructions
- Able and willing to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nordland Hospital Trust | Bodø | Norway | Unknown status |
| University Hospital of North Norway | Tromsø | Norway | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.